Cytokeratins are expressed in different types of epithelial cells in certain combinations of polypeptides of the acidic (type I) and basic (type II) subfamilies, showing "expression pairs." We have examined in vitro the ability of purified and denatured cytokeratin polypeptides of human, bovine, and rat origin to form the characteristic heterotypic subunit complexes, as determined by various el...

INTRODUCTION A collision tumor is the meeting and eventual intermingling of two malignant neoplasms arising from independent topographical sites. Collision metastasis of carcinomas in the lymph nodes is a rare event. A literature search revealed only three cases of such a collision metastasis of prostatic and urothelial carcinoma, and only one of those cases had used immunohistochemical stains ...

BACKGROUND The vast majority of uterine cervical malignancies are primary carcinomas, and secondary neoplasms that metastasize to the uterine cervix from a distant organ are uncommon. Although relatively rare, metastases to the uterine cervix from a primary colon cancer have been reported. We report a rare case of metastatic carcinoma originating from a cecal adenocarcinoma with an unusual cyto...

Introduction. Currently, there are limited papers on changes in the pseudostratified ciliated columnar epithelium of sinonasal tract chronic inflammatory processes, particularly basal cell hyperplasia. The latter is similar to dysplasia varying severity stratified squamous nonkeratinized epithelium. Studying can clarify histogenesis various epithelial tumors tract, including papillomas. researc...

Introduction . The feasibility and risks of glucocorticosteroids (GCS) in severe alcoholic hepatitis (SAH) are actively discussed, there is a real need to develop new biomarkers both determine indications for the GCS use evaluate their effectiveness. Аim Тo effectiveness SAH using marker hepatocyte apoptosis inflammatory cytokines along with traditional laboratory parameters. Materials methods ...