OBJECTIVE The impact of cytomegalovirus reactivation during critical illness remains unclear and studies investigating prophylaxis in cytomegalovirus seropositive patients are being considered. This study investigates the association between cytomegalovirus seropositivity and outcome in a large population of nonimmunocompromised critically ill patients. DESIGN Cytomegalovirus serostatus was d...

Background: Drug-induced hypersensitivity syndrome (DIHS) can be associated with cytomegalovirus (CMV) infection, besides induced by drugs. We report a case of DIHS prolonged atypical clinical features and vasculitis precipitated drug allergy, CMV, other viral infections.

the aim of this study was to evaluate the immune system and lymphocyte function in 41 iranian β-thalassemic patients and 50 controls, ages ranging from 2 to 18 years. the patients consisted of 20 splenectomized and 21 non-splenectomized patients. they were treated with desferal, and had received repeated blood transfusion. laboratory investigations included measurement of total t lymphocytes, a...

conclusions only 11% of kidney transplant patients, even with a successful transplantation of the kidney and with an acceptable performance of the transplanted kidney, had an adequate level of vitamin d. although, we did not find any significant association between vitamin d levels and cmv infection during a 4-month follow-up after kidney transplantation. it was observed that, compared with the...

cytomegalovirus is the most important pathogen affecting transplant recipients and causing significant morbidity and morbidity. the prevalence of cmv  infections in transplant recipient varies from country to country.  the aim of this study was to determine the prognostic value of pcr assay for cmv  detection in patients before keratoplasty.  a total of 23 patient samples enrolled in this study...

objective(s):human cytomegalovirus (hcmv) remains a major morbidity and mortality cause in immuno suppressed patients. therefore, significant effort has been made towards the development of a vaccine. in this study, the expression of the pp65 and gb fusion peptides and fc domain of mouse igg2a as a novel delivery system for selective uptake of antigens by antigen-presenting cells (apcs) in pich...

background: cytomegalovirus (cmv), a problematic virus in solid organ transplant recipients (sotr) such as liver, can worsen overall mortality and transplant outcome, so its prevention and treatment is a key of success in such patients. this study is aimed to compare the efficacy of ganciclovir (gcv) and valganciclovir (vgc) for prevention and treatment of infection with cmv. materials and meth...

OBJECTIVES To define the frequency of cytomegalovirus disease among kidney transplant patients in an intensive care unit in which this complication was suspected and to identify predisposing factors and their possible impact on clinical outcome. METHODS Retrospective observational study in which kidney transplant patients over the age of 18 years were hospitalized for any reason in an intensi...