نتایج جستجو برای: cytotoxicity tests

تعداد نتایج: 380773  

Journal: :Applied sciences 2021

In this work, a review about the applicability of eutectic solvents, mainly deep solvents (DES) and natural (NADES), for extraction bioactive compounds from products has been carried out. These alternative have shown not only to high yields but also be environmentally friendly, exhibiting very low or almost no toxicity, compared conventional organic solvents. The last trends main methods that m...

Journal: :iranian journal of basic medical sciences 0
ahmad mohammadi-farani novel drug delivery research center, faculty of pharmacy, kermanshah university of medical sciences, kermanshah, iran 2 department of pharmacology, toxicology and medical services, faculty of pharmacy, kermanshah university of medical sciences, kermanshah, iran alireza foroumadi department of medicinal chemistry, faculty of pharmacy and pharmaceutical sciences research center, tehran university of medical sciences, tehran, iran monireh rezvani kashani students research committee, kermanshah university of medical sciences, kermanshah, iran 5 department of medicinal chemistry, faculty of pharmacy, kermanshah university of medical sciences, kermanshah, iran alireza aliabadi novel drug delivery research center, faculty of pharmacy, kermanshah university of medical sciences, kermanshah, iran department of medicinal chemistry, faculty of pharmacy, kermanshah university of medical sciences, kermanshah, iran

objective(s):according to the prevalence of neoplastic diseases, there is a deep necessity for discovery of novel anticancer drugs in the field of medicinal chemistry. in the current study, a new series ofphenylthiazole derivatives(compounds 4a-4f) was synthesizedand theiranticancer activity was assessed in vitro. materials and methods:all synthesized derivatives were evaluated towards three hu...

Journal: :journal of medical bacteriology 0
rokhsareh sadeghi department of periodontics, faculty of dentistry, shahed university, tehran, ir iran. parviz owlia molecular microbiology research center, shahed university, tehran, ir iran. roya yaraee department of immunology, medical school, shahed university, tehran, ir iran. fatemeh sharif general dentist, educated student in faculty of dentistry, shahed university, tehran, ir iran. ferial taleghani department of periodontics, faculty of dentistry, shahed university, tehran, ir iran.

b ackgro un d : the antimicrobial activity of silver nanoparticles has been investigated in medical fields in recent years, but there are few studies regarding its effect on oral microorganisms. the aim of the present study was to evaluate the in vitro antimicrobial and toxicity properties of nanosilver against two dental plaque microorganisms  and human gingival fibroblast (hgf) cell line. me ...

Journal: :nanomedicine research journal 0
neamat karimi department of pharmacology, school of pharmacy, ardabil university of medical sciences, ardabil, iran shahab bohlooli department of pharmacology, school of pharmacy, ardabil university of medical sciences, ardabil, iran mohammad mazani department of pharmacology, school of pharmacy, ardabil university of medical sciences, ardabil, iran

objective(s): the aim of this study was to determine cytotoxic effect of nanoliposomal form of lyophilized aqueous extract of ecballium elaterium fruit on gastric cell line (ags) using cell viability tests. methods: an aqueous extract of the fruits of ecballium elaterium was prepared. nanoliposomal form was also prepared by thin-film hydration method and stability size was determined by sem. th...

Journal: :Journal of Materials Science 2022

The corrosion resistance and biocompatibility of a novel Fe50Cr18Mo10C20Si2 metallic glass (Fe–MG), are studied by electrochemical measurements indirect contacting cytotoxicity assays for biomedical applications. In Hank’s solution, the Fe–MG shows better than SS316L, evidenced larger polarization in potentiodynamic impedance spectroscopy (EIS) tests, lower amounts released ions during immersio...

2015
Kimberly H. Harrington Chelsea J. Gudgeon George S. Laszlo Kathryn J. Newhall Angus M. Sinclair Stanley R. Frankel Roman Kischel Guang Chen Roland B. Walter Ken Mills

The CD33/CD3-bispecific T-cell engaging (BiTE) antibody construct, AMG 330, potently lyses CD33+ leukemic cells in vitro. Using specimens from 41 patients with acute myeloid leukemia (AML), we studied the factors that might contribute to clinical response or resistance. For this purpose, thawed aliquots of primary AML samples were immunophenotypically characterized and subjected to various dose...

Journal: :Journal of hazardous materials 2010
Sean M Cook Winfred G Aker Bakhtiyor F Rasulev Huey-Min Hwang Jerzy Leszczynski Jessica J Jenkins Vincent Shockley

Assessment of C(60) nanotoxicity requires a variety of strategies for dispersing it into biological systems. Our objective was to determine organic solvent/surfactant combinations suitable for this purpose. We used Escherichia coli (ATCC# 25254) to determine the cytotoxicity of C(60) in solvents at concentrations up to 100 ppm. In this preliminary study we hypothesized that C(60) toxicity is di...

2013
Madhulika Srikanth Ramazan Asmatulu S. Y. Yang

In the recent years, the use of nanomaterials has increased exponentially. In spite of the extensive research in this field, some areas are not completely understood, one of them being nanosafety. Because of their size and shapes, these nanomaterials have the ability to be easily absorbed in the biological and the ecological systems and interfere with them by hampering smooth functioning. In th...

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