hutchinson-gilford progeria syndrome (hgps) is a rare premature ageing disorder that is characterized by accelerated degenerative changes of the cutaneous, musculoskeletal and cardiovascular systems. mean age at diagnosis is 2.9 years and generally leading to death at approximately 13 years of age due to myocardial infarction or stroke. orthopedic manifestations of hgps are multiple and shoulde...

There is great uncertainty regarding the relation between degenerative changes and age. This article aimed to summarize and quantify association between age and degenerative changes in the cervical spine by using the common imaging techniques. A structured literature search was conducted on medline (PubMed), Google Scholar and other databases. The search had no period or language restrictions. ...

Erythropoietin (EPO) is a chemokine hormone that is widely distributed throughout the body including nervous system. For last years its role as cytokine involved in many physiological processes out of the bone marrow has been suggested. Moreover, it plays a very important role in CNS as potential neuroprotective agent. There is much evidence that EPO protects neuronal cells in vitro and in vivo...

background: previous researches about the effects of epididymal obstruction on the testes are contradictory, and the mechanism harmful effect of male duct system obstruction on seminiferous tubules still remains unclear. objective: the aim of this study was to investigate the effects of epididymal obstruction in prepubertal rats on the testis. materials and methods: 15 days of age, the young ra...

schwannoma(neurilemmoma) is a benign tumor originates from schwann cells. ancient (degenerated) schwannoma is a long-standing schwannoma with degenerative changes. head and neck region is one of the most common sites for nerve sheath tumors but intraosseous schwannoma is rare. the mandible is the most common site of occurrence for this lesion. we report a rare case of intraosseous ancient schwa...

Myiasis is a condition in which fly maggots feed off, and develop in, the tissues of living organisms. True myiasis results from files deliberately laying eggs in or on the tissues. There are two forms of myiasis: obligate, in which it is necessary for the maggots to feed on living tissues, and facultative, where files opportunistically take advantage of wounds or degenerative necrotic conditio...

A retrospective review was done to evaluate the importance of degenerative endometrial debris accompanied with benign-looking endometrial cells in Papanicolaou (Pap) smears. In total, 306 patients were divided into 2 groups according to the absence (group 1) or presence (group 2) of endometrial debris. Eighty-one (26.5%) patients received histologic follow-up. The biopsy rate for premenopausal ...