Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. Recent studies have provided evidences of strong correlation between the expression levels of these family members and the malignant transformation as well as the resistance to cancer therapy. Mechanistically...

objective: dietary changes playmajor risk roles in oxidative stress andcardiovascular disease and modulate normal metabolic function. the present study was designed to investigate the ameliorative potential of different extracts of hemidesmus indicus to experimental high-fat diet in wistar rats, and their possible mechanism of action.  materials and methods: male wistar rats were divided into 6...

employee engagement at work is a concept that recently entered in organizational discussions in past two decades. engaged employees are happy, energetic and productive employees that are willing to invest the discretionary effort through the work and organizational roles. previous literatures show that employee engagement at work is affected by different personal, vocational and organizational ...