Sub-diagnostic depression, sleep, and circadian rest-activity rhythm (CAR) syndromes are common in late-life, but their characteristics, prevalence, and relations to future depression are unclear. We characterized commonly occurring sleep, CAR, and depressive sign/symptom patterns using a data-driven approach applied to a large population-based study of older men. We next examined relationships...

Objectives. Determine the relationship between depressive symptom clusters and neuropsychological test performance in an elderly cohort of cognitively normal controls and mild Alzheimer's disease (AD). Design. Cross-sectional analysis. Setting. Four health science centers in Texas. Participants. 628 elderly individuals (272 diagnosed with mild AD and 356 controls) from ongoing longitudinal stud...

BACKGROUND Adolescents rarely seek psychiatric help; they even hesitate to disclose their feelings to their parents. However; the adolescents especially the females experience depressive symptoms more frequently than general population. Do they experience classic depressive symptoms? Are there symptoms specific to this subpopulation? AIM OF THE STUDY Through this study, the authors aimed to e...

Among multiple etiological factors of depressive disorders, childhood maltreatment (CM) gains increasing attention as it confers susceptibility for depression and predisposes to chronicity. CM assumedly inhibits social-cognitive development, entailing interactional problems as observed in chronic depression (CD), especially in affective theory of mind (ToM). However, the extent of CM among CD p...

BACKGROUND/AIM While poor sleep quality and sleep problems are signs of depression in adolescents, depressive symptoms among this age group further deteriorate sleep quality. The aim of this study was to explore the relationship between sleep quality and depressive symptoms in adolescents of 14 to 20 years of age. MATERIALS AND METHODS This study was conducted with a descriptive and cross-sec...

The relation of marital complaints to family history was examined in a sample of 1,624 psychiatric outpatients. Marital complaints were recognized to be an aspect of a broader "depressive spectrum disorder" with distinctive age, gender, alcohol, and neurotic depressive symptom characteristics; however, holding constant the depressive spectrum characteristics, a specific independent relation of ...

BACKGROUND Little is known about seasonality of specific depressive symptoms and anxiety symptoms in different patient populations. This study aims to assess seasonal variation of depressive and anxiety symptoms in a primary care population and across participants who were classified in diagnostic groups 1) healthy controls 2) patients with a major depressive disorder, 3) patients with any anxi...

BACKGROUND Little is known about whether cognitive/affective depressive symptoms or somatic/affective depressive symptoms are associated with inflammation in heart failure (HF), or that the relation is confounded with disease severity. AIM To examine the association between depressive symptom dimensions in HF patients with inflammatory markers cross-sectionally and prospectively, while adjust...

BACKGROUND In elderly general population sub-syndromal clinically significant levels of depressive symptoms are highly prevalent and associated with high co-morbidity and increased mortality risk. However changes in depressive symptoms over time and etiologic factors have been difficult to characterise notably due to methodological shortcomings. Our objective was to differentiate trajectories o...