The reagent (S)-5-methoxy-2-[[(4-methoxy-3, 5-dimethyl-2-pyridinyle-methyle] sulfinyle]-1H-benzimidazole gives greenish yellow coloration with V (V) as well as Co (II) in basic medium. This observation is used for the simultaneous determination of both the metal ions using Zero and second order derivative spectrophotometry. Optimum conditions were established for this determination. Job’s and m...

The degradation behavior of cefixime trihydrate was investigated under different stress conditions of acidic hydrolysis, alkaline hydrolysis and oxidation using spectrophotometry. Stability indicating spectrophotometric methods were developed that could separate the drug from its degradation products formed under these stress conditions. The UV spectral characteristics of the drug and degraded ...