Background: Cognitive disorders are symptoms of degenerative neuronal diseases such as Alzheimer’s disease (AD). This study evaluated the effects a mixture Gastrodiae elata (GE) and Glycyrrhizae uralensis (GU) (GGW) on scopolamine-treated cognitive function in vivo. Methods: To induce memory impairment disorder, C57BL/6 mice were intraperitoneally administered scopolamine. In experimental perio...

Transcription of the brain-derived neurotrophic factor (BDNF) gene is regulated in a calcium- and neuron-selective manner; however, the mechanisms that underlie this selectivity are not known. We have characterized a new calcium-response element, CaRE1, that is required for activity-dependent transcription of BDNF exon III and have cloned a transcription factor, CaRF, that activates transcripti...

Introduction: Ramadhan fasting increases mental and physical health. The study aims to evaluate the effect of on fatigue, sleepiness, depression anxiety mood, quality life (QoL), Brain-derived neurotrophic factor (BDNF) serum level.
 Methods: Twenty participants are included in group (FG), nineteen non-fasting (NFG). Fatigue severity scales (FSS), fatigue VAS, Epworth sleepiness scale (ESS...