BACKGROUND Localized scleroderma is characterized by a thickening of the skin from excessive collagen deposits. It is not a fatal disease, but quality of life can be adversely affected due to changes in skin appearance, joint contractures, and, rarely, serious deformities of the face and extremities. We present six cases of localized scleroderma in face from our surgical practice. METHODS We ...

Warfare-related torso/abdominal wounds are often unique and complex and can pose a significant reconstructive challenge. The objective of this manuscript is to report the unique and successful management of a complex warfare-related abdominal wound. A dermal regenerate template in combination with negative pressure wound therapy was used to reconstitute lateral abdominal wall integrity after ra...

OBJECTIVES/HYPOTHESIS To report a technique for septal perforation repair that does not rely on intraoperative mucosal closure of the perforation defect. STUDY DESIGN Case series with prospective and retrospective data collection. METHODS Nine patients received multilayer interposition grafts and no attempt at intraoperative mucosal closure for repair of septal perforations. Eight patients ...

INTRODUCTION One of the most devastating complications of deep burn injuries to the hand and finger is the exposure of joint, tendon, and neurovascular structures. The inevitable consequence of such injuries is severe deformity, often requiring joint fusions and digital amputations. Complicating this scenario is the anatomic limitation of few local and reliable soft tissue flaps available for t...

Relevance . Autografts are nowadays the gold standard for soft tissue augmentation and gingival recession coverage. However, as this method has a number of significant disadvantages, xenografts various origins more frequently used in dental practice. The study aimed to conduct comparative morphological assessment crosslinked non-crosslinked xenogenous scaffold biointegration quality at differen...

Background Treatment of patients with post-traumatic severe and chronic wounds poses many challenges. A large number dermal analogs have been invented in an effort to overcome these Matriderm, a biosynthetic analog, is made from bovine collagen elastin. The aim our study was prove the effectiveness MatriDerm® combined skin grafting versus alone difficult-to-heal wounds.
 Material Methods: ...

This report describes favorable outcomes in 9 patients with skin avulsion injuries of the extremities who underwent full-thickness skin grafting and basic fibroblast growth factor (bFGF) application. Following removal of contaminated subcutaneous fat tissue on the inside of skin, the avulsed skin was processed into a full-thickness skin graft, with as much of the skin used as possible irrespect...

hazardous chemicals may enter the body by inhalation, ingestion, injection or dermal absorption. these exposure routes constitute the overall exposure burden on the body. most occupational exposure studies have focused on measurement of the concentration of air-borne contaminants and other possible routes of exposure are often overlooked. several studies have already highlighted the importance ...

Based on immunomodulatory, osteogenic, and pro-angiogenic properties of adipose-derived stem cells (ASCs), this study aims to assess the safety and efficacy of ASC-derived cell therapies for clinical indications. Two autologous ASC-derived products were proposed to 17 patients who had not experienced any success with conventional therapies: (1) a scaffold-free osteogenic three-dimensional graft...

OBJECTIVE Split skin graft reconstruction of scalp defects often leaves an obvious contour defect. Here, we aimed to demonstrate the use of a decellularized extracellular matrix biomaterial, termed ovine forestomach matrix (OFM), as a substrate for split-thickness skin grafts (STSGs) for scalp reconstruction. METHODS Following full-thickness tumor excision, OFM was applied directly to skull p...