Argyria is a rare cutaneous condition due to dermal silver deposition leading to irreversible blue-grey discoloration. Acute radiation dermatitis (RD) is an expected toxicity in patients undergoing radiotherapy but it is unknown to what extent argyria affects the onset and severity of RD. We report a patient with argyria treated with concurrent chemoradiotherapy for Merkel cell carcinoma who ex...

Phthalates are used in commercial products as softners of plastics, solvents in perfumes and additives to hair sprays, lubricants and insect repellents. The wide spread use of phthalate results in multiple human exposure routes i.e., ingestion, inhalation and dermal exposure. In the present review, a detailed account of respiratory toxicity, phthaltes is high given their use in a vast range of ...

It is well recognized that physical and chemical properties of materials can alter dramatically at nanoscopic scale, and the growing use of nanotechnologies requires careful assessment of unexpected toxicities and biological interactions. However, most in vivo toxicity concerns focus primarily on pulmonary, oral, and dermal exposures to ultrafine particles. As nanomaterials expand as therapeuti...

Background: The rectum is the lower part of colon. Its cancer third most common worldwide. Aim: To determine frequency and severity acute perineal skin reactions in rectal patients at completion preoperative pelvic radiotherapy. Study Design: Descriptive case series. Methodology: conducted Department Clinical Oncology, Shaukat Khanum Memorial Cancer Hospital Multan. Patients (n=96) were enrolle...