BACKGROUND Both obstructive sleep apnea syndrome (OSAS) and coronary artery calcification (CAC) are considered to be related with the presence of coronary artery disease (CAD). In this study we evaluate the association between OSAS and presence of subclinical atherosclerosis assessed by tomographic coronary calcium score in patients who had OSAS but no history of known CAD. METHODS Seventy-th...

BACKGROUND Desaturation occurs for many reasons under anaesthesia, some rare and obscure, and many potentially life threatening. The rapidity with which the cause is determined and appropriate management is instituted varies considerably between anaesthetists. OBJECTIVES To examine the role of a previously described "core" algorithm COVER ABCD-A SWIFT CHECK, supplemented by a specific sub-alg...

Toraldo and colleagues (December 2005)1 are to be congratulated on their endeavor to identify daytime variables that are predictive of nocturnal desaturation in COPD patients, a field in which many attempts have failed. However, we think that some points are worth addressing. First, despite the plethora of data presented by Toraldo et al,1 it does not greatly contribute to the evidence base of ...

Objective. To assess the diagnostic ability of WristOx 3100 using its three different recording settings in patients with suspected obstructive sleep apnea syndrome (OSAS). Methods. All participants (135) performed the oximetry (three oximeters WristOx 3100) and polysomnography (PSG) simultaneously in the sleep laboratory. Both recordings were interpreted blindly. Each oximeter was set to one o...

Rationale: Continuous positive airway pressure (CPAP) is the treatment of choice in patients with Symptomatic Obstructive Sleep Apnea Syndrome (OSAS). Recently, Mandibular Advancement Devices (MAD) are used in the treatment of OSAS. Objective: Investigate the efficacy of the Orthoapnea MAD in patients with mild or moderate OSAS in adults. Methods: This is a prospective study. Patients diagnosed...

OBJECTIVE To identify the predictive factors of oxygen desaturation during the six-minute walk test (6MWT) in patients with cystic fibrosis (CF). METHODS Prospective cross-sectional study involving clinically stable patients with CF aged > or = 10 years. The patients were submitted to nutritional evaluations, oral glucose tolerance tests, pulmonary function tests, chest X-rays and 6MWTs. RE...

The incidence of oxygen desaturation (less than 91%) was measured by pulse oximetry during recovery from outpatient dental anaesthesia in 120 ASA grade I and II children. Alternate cases were given supplementary oxygen 5 litre min-1 by mask. Eighteen of 60 children (30%) given air and 14 of 60 (23%) given oxygen exhibited desaturation (P greater than 0.05). Desaturation was more likely to occur...

OBJECTIVE We hypothesized that intermittent hypoxia might influence serum substance P levels, and that this effect might in turn contribute in excessive daytime sleepiness (EDS) in patients with obstructive sleep apnea syndrome (OSAS). PATIENTS AND METHODS Fifty-five patients with newly diagnosed OSAS and 15 age-matched nonapneic control subjects were enrolled in this study. Full polysomnogra...

BACKGROUND Treatment of Robin sequence is often either invasive or of unproven effectiveness. The pre-epiglottic baton plate (PEBP) is a well-studied alternative, yet is not widely applied internationally. We report on a prospective 3-center cohort study investigating this treatment. Based on an agreed protocol, parents of infants with Robin sequence referred to participating centers were offer...