BACKGROUND Smoking, alcohol use, diet, body mass index (calculated as weight in kilograms divided by height in meters squared), and physical activity have been studied independently in relation to pancreatic cancer. We generated a healthy lifestyle score to investigate their joint effect on risk of pancreatic cancer. METHODS In the prospective National Institutes of Health-AARP Diet and Healt...

BACKGROUND The prevailing efforts for cardiovascular disease (CVD) prevention focused on treatment of common CVD risk factors rather than primordial prevention of risk factors through health behaviors. The previously validated Healthy Heart Score effectively predicted the 20-year risk of CVD in midadulthood; however, it is unknown whether this risk score is associated with clinically relevant C...

the present study aimed to evaluate the distributions of high-sensitivity c-reactive protein, tc-hdl ratio and 10-year risk of cardiovascular diseases among iranian adult population. we conducted a cross-sectional study on a total of 2125 adults aged 25 to 65. data of the third national surveillance of risk factors of non-communicable diseases (surfncd-2007) was used. anthropometric indices, bl...

conclusions age, injury severity, injured body region, and hospital-acquired infections are important determinants of trauma outcome in our center. timely recognition of factors affecting trauma mortality is crucial for monitoring changes of trauma quality of care. our findings suggest the need to allocate resources for trauma prevention along with a potential focus on reducing in-hospital comp...

INTRODUCTION To develop and test a diabetes risk score to predict incident diabetes in an elderly Spanish Mediterranean population at high cardiovascular risk. MATERIALS AND METHODS A diabetes risk score was derived from a subset of 1381 nondiabetic individuals from three centres of the PREDIMED study (derivation sample). Multivariate Cox regression model ß-coefficients were used to weigh eac...

A promising hypertension risk prediction score using data from the US Framingham Offspring Study has been developed, but this score has not been tested in other cohorts. We examined the predictive performance of the Framingham hypertension risk score in a European population, the Whitehall II Study. Participants were 6704 London-based civil servants aged 35 to 68 years, 31% women, free from pre...