BACKGROUND Dunnigan type Familial Partial Lipodystrophy (FPLD) is characterized by loss of subcutaneous fat from the limbs and excessive accumulation on the visceral adipose tissue (VAT). Affected individuals have insulin resistance (IR), diabetes, dyslipidemia and early cardiovascular (CV) events, due to their imbalanced distribution of total body fat (TBF). Epicardial adipose tissue (EAT) is ...

Aims and objectives: To compare the accuracy of prediction of osteoporosis in digital panoramic radiography with Dual Xray absorptiometry (DEXA) scans and serum investigations such, as calcium, phosphorous, alkaline phosphatase in postmenopausal women. The objective of the study is to detect the appearance of eroded mandibular cortex (cortical shape), inferior cortical width appearance on Digit...

Background Osteoporosis is a common complication of Rheumatic diseases. The association between osteoporosis and rheumatoid arthritis clearly demonstrated while this still debated as well for the screening by Dual-Energy X-Ray Absorptiometry (DEXA) or to demonstrate an increased risk fracture on radiography in population Psoriatic Arthritis (PsA). prevalence fragility fractures reported medical...

The aim of this study was to further explore the use of magnetic resonance imaging (MRI), magnetic resonance angiography (MRA), and dual-energy X-ray absorptiometry (DEXA) to assess bone formation and blood circulation in a pedicled bone graft substitute. In 14 Wistar rats, initially 10 weeks old, heterogeneous demineralized femur bone matrix implants were wrapped in pedicled adductor thigh mus...

In the rat, urinary concentrating ability develops progressively during the third postnatal (P) week and nearly reaches adult level at weaning (P21) governed by a rise in circulating glucocorticoid. Elevated extracellular osmolality can lead to growth arrest of epithelial cells. We tested the hypothesis that supranormal exposure of rat pups to glucocorticoid before the endogenous surge enhances...

We developed and tested a novel method for perfusing parts of human liver to study uptake and handling of drug-targeting preparations. These preparations, designed for the treatment of liver fibrosis in man, have been extensively studied in animals, but little is known about the uptake and handling by human livers. Human liver tissue was obtained from livers procured from multiorgan donors and ...

OBJECTIVE To validate different methods for estimating HIV/Aids patients' body fat: total body skinfold thickness, central (trunk) skinfold thickness, peripheral (limb) skinfold thickness, waist circumference (WC) and waist-to-hip ratio (WHR). Dual-energy X-ray absorptiometry (DEXA) and computed tomography of the abdomen (CTA) were used as the gold standard. METHODS An analysis was done on 15...

Agents with stem cell-toxic potential are frequently used for salvage therapy of Hodgkin's disease (HD) and high-grade non-Hodgkin's lymphoma (NHL). Because many patients with relapsed or refractory lymphoma are candidates for autologous progenitor cell transplantation, possible toxic effects of salvage chemotherapy on progenitor cells must be taken into account. In a retrospective study, we ha...

OBJECTIVE To evaluate the sensitivity and specificity of different cutoff points of body mass index for predicting overweight/obesity according to body fat values estimated by DEXA among Brazilian adolescents. METHODS Cross-sectional study including 229 male adolescents aged 10-15 years, in which body adiposity and anthropometric measures were assessed. Nutritional status was classified by BM...

OBJECTIVE The study tested the hypothesis that females who sustain stress fractures of cancellous bone have decreased bone density. DESIGN A retrospective, controlled, cross-sectional study. SETTING The setting of the study was a tertiary care center for Women's Sports Medicine. PATIENTS 20 female patients under the age of 40 who had suffered a stress fracture and who had a positive diagn...