Exogenous Cushing’s syndrome is a collection of symptoms and clinical signs due to elevated levelsof glucocorticoids (cortisol) in the blood because prolonged consumption glucocorticoid drugs.Glucocorticoids were introduced 1950s have been used for anti-inflammatory treatment. Withdrawalof can lead complications secondary adrenal insufficiency caused by suppression ofthe Hypothalamic-Pituitary-...

normal 0 false false false en-us x-none ar-sa background: coronary artery bypass graft is one of common cardiac surgeries which unfortunately accompany with some adverse events such as delirium. proinflammatory processes play an important role in pathogenesis of post-operative delirium. therefore, the effect of dexamethasone (dex) on post-operative delirium after cardiac surgery was evaluated. ...

objective(s) the aim of this study was to evaluate the effects of dexamethasone on striatal dopaminergic, glutamatergic and gamma amino butyric acid (gaba) ergic neurotransmission in normal and parkinsonian rats. materials and methods dexamethasone (0.15, 0.30, 0.60 and 0.8 mg/kg) was administered to normal or parkinsonian rats (i.p.) followed by the analysis of the striatal neurotransmitters c...

conclusions dexamethasone 8mg is a better anti-emetic agent than metoclopramide for the prevention of post-operative nausea and vomiting after laparoscopic cholecystectomy. objectives this study evaluates the prophylactic anti-emetic effect of dexamethasone in comparison with metoclopramide and placebo for the prevention of post-operative nausea and vomiting in patients undergoing elective lapa...

The idiopathic retinal vasculitis, aneurysms and neuroretinitis (IRVAN) syndrome is a disease characterized by multiple retinal macroaneurysms, neuroretinitis and peripheral capillary nonperfusion. Visual loss may result from either ischemia-related complications or macular involvement. Treatment is not always rewarding. We report a case with stage 2 IRVAN syndrome who was successfully treated ...

background croup, or acute laryngotracheobronchitis, is the most common cause of upper airway obstruction in children. objectives in this study, the efficacies of intramuscular and oral dexamethasone administration are compared for treatment of croup. patients and methods this is a single-blind randomized trial involving 68 children divided into two groups, the first group received 0.6 mg/kg in...

salivary mucocele is a common lesion derived from minor salivary glands with various surgical or non-surgical treatment modalities. to evaluate the effect of a highly potent corticosteroid (dexamethasone) in the management of salivary mucocele, we performed intralesional injection of dexamethasone in nine patients with labial mucocele. complete healing of lesions observed in seven of nine patie...

Secondary bacterial infections post-COVID infection posed a major challenge to the healthcare settings during COVID pandemic. We present case of an 81-year-old patient who was initially admitted for pneumonia in tertiary care hospital and managed with course dexamethasone had good outcome. However, post-discharge, developed symptoms productive cough, hemoptysis shortness breath. Evaluation reve...