MicroRNAs (miRNAs) are small RNA molecules consisting of approximately 22 nucleotides that engaged in the regulation various bio-processes. There is growing evidence miR-29 a key regulator hepatic lipid metabolism. Mimics and inhibitors bta-miRNA29d-3p were transiently transfected bovine mammary epithelial cells (BMECs) to reveal on accumulation BMECs. Results showed overexpression significantl...

Diacylglycerol acyltransferases (DGAT) catalyze the final and rate-limiting step of triacylglycerol (TAG) biosynthesis in eukaryotic organisms. DGAT genes have been identified in numerous organisms. Multiple isoforms of DGAT are present in eukaryotes. We previously cloned DGAT1 and DGAT2 genes of tung tree (Vernicia fordii), whose novel seed TAGs are useful in a wide range of industrial applica...

Article history: Received 27 January 2011 Received in revised form 1 April 2011 Accepted 19 April 2011 Diacylgycerol acyltransferase (DGAT) plays a key modulatory role in animal fat deposition. Intramuscular fat (IMF) content and backfat thickness (BFT) were important factors in establishing pork quality. Therefore, the objectives of the current study were to elucidate the relationship between ...

It has been suggested that traits associated with fitness, such as fertility, may have proportionately more genetic variation arising from non-additive effects than traits with higher heritability, such as milk yield. Here, we performed a large genome scan with 408,255 single nucleotide polymorphism (SNP) markers to identify chromosomal regions associated with dominance and epistatic (pairwise ...

The acyl-CoA:diacylglycerol acyltransferase (DGAT) enzymes DGAT1 and DGAT2 catalyze the final step in triglycerides biosynthesis. This study examined the relationships of baseline phenotypes and the common polymorphisms in DGAT1 and DGAT2 with the lipid responses to niacin.Lipid responses in Chinese patients with dyslipidemia treated with the extended release (ER) niacin/laropiprant combination...

Polymorphisms located in the genes ABCG2, DGAT1, LEP, PRLR, RORC, CAPN1 and CAST previously have been associated with milk or meat production traits. In this study, these polymorphisms were examined for significant effects on reproductive traits [age at puberty (AGECL), post-partum anoestrus interval (PPAI) and the ability ovulate prior to weaning (PW)] and on a panel of correlated traits such ...

Abstract Background Fat deposition is an important economic consideration in pig production. The amount of fat pigs seriously affects production efficiency, quality, and reproductive performance, while also affecting consumers’ choice pork. Weighted gene co-expression network analysis (WGCNA) effective genetic studies. Therefore, this study aimed to identify modules that co-express genes associ...

this experiment was aimed to study the association between the dgat1 k232a polymorphism and milk production traits and somatic cell score (scs) in iranian holstein dairy cows. the records of 408 animals from five dairy herds were randomly identified and then genomic dna was extracted from blood using the modified-salting method described by miller. rflp-pcr was performed to obtain all the polym...