In skeletal muscles, the sarcolemma is possibly stabilized and protected against contraction-imposed stress by intermediate filaments (IFs) tethered to costameric sarcolemma. Although there is emerging evidence that plectin links IFs to costameres through dystrophin-glycoprotein complexes (DGC), the molecular organization from plectin to costameres still remains unclear. Here, we show that plec...

The dystrophin-glycoprotein complex (DGC) is a sarcolemmal complex whose defects cause muscular dystrophies. The normal function of this complex is not clear. We have proposed that this is a signal transduction complex, signaling normal interactions with matrix laminin, and that the response is normal growth and homeostasis. If so, the complex and its signaling should be altered in other physio...

INTRODUCTION Gastric cancer (GC) is the third leading cause of cancer death worldwide, and is divided histologically in diffuse gastric cancer (DGC) and intestinal gastric cancer (IGC). Multiple risk factors have been associated with GC in different populations. The objective was to analyze the risk factors associated to DGC and IGC in a population from the western region of Mexico. MATERIAL ...

Commentary Identification and characterization of the vast variety of hippo-campal principal neurons and interneurons are necessary to understand the role that each cell type plays in the complex network alterations leading to epilepsy (1). Over several decades, research has focused on which cells are necessary, sufficient, or extraneous for hippocampal dysfunction often observed in animal mode...

The dystrophin-glycoprotein complex (DGC) is a multimeric transmembrane protein complex first isolated from skeletal muscle membranes (1). The central protein of the DGC is dystroglycan (Fig. 1). In addition to skeletal muscle, dystroglycan is strongly expressed in heart and smooth muscle, as well as many non-muscle tissues including brain and peripheral nerve. In vertebrates, dystroglycan is g...

The distributed Goppa coded spatial modulation (DGC-SM) scheme is proposed in cooperative scenarios. In the DGC-SM scheme, relay chooses partial information from source by using idea of selection, and then re-encodes selected information. At destination, a code obtained corresponding to each selection. order get best possible code, an optimal selection algorithm at relay. algorithm, all selecti...

Document-grounded conversation (DGC) is a natural language generation task to generate fluent and informative responses by leveraging dialogue history document(s). Recently, DGCs have focused on fine-tuning using pretrained models. However, these approaches problem in that they must leverage the background knowledge under capacity constraints. For example, maximum length of input limited 512 or...

The contribution of this paper is twofold. First a distributed garbage collector (DGC) is presented that is optimized for remote method invocation in reliable networks, such as current clusters of workstations. Since the algorithm does not require extra acknowledgement messages, even while collecting, it does not increase the latency of a remote call. Then it is discussed how several DGCs can c...

Biofilms formed by bacterial pathogens are responsible of more than 70% of all infections in developed countries and are less sensitive to treatments with antimicrobial agents. The ubiquitous second messenger 3', 5'-cyclic diguanylic acid (c-di-GMP) is used in most bacteria to control the switch to the biofilm lifestyle; c-di-GMP has no counterpart in eukaryotic cells and thus it is an ideal ta...

The recent advances in the field of Ambient Intelligence (AmI) have raised a new generation of distributed applications with sophisticated characteristics. AmI applications are distributed among mobile devices interconnected by wireless communication media that allow them to interact spontaneously with other devices the environment forming mobile ad hoc networks. Although many distributed garba...