Estrogen might play an important role in the pathogenesis of diabetes mellitus type 2. Estrogens inhibit diabetes via distinct mechanisms particularly by reducing both hyperglycemia and plasma insulin levels. Estrogen exerts its physiological effects mainly through estrogen receptors including α and β types. Estrogen receptors are found in many tissues that participate in the pathogenesis of ty...

AIMS Population surveys of Type 2 diabetes mellitus and obesity conducted in Samoa over three decades have used varying methodologies and definitions. This study standardizes measures, and trends of Type 2 diabetes mellitus and obesity for 1978-2013 are projected to 2020 for adults aged 25-64 years. METHODS Unit records from eight surveys (n = 12 516) were adjusted to the previous census for ...

to determine the relation between birth weight and age of presentation of type 1 diabetes and assess its risk factors, a case-control study was done on all diabetic patients under the age of 15, who were registered in shiraz diabetic center or admitted in namazi hospital. a case group of 87 diabetic patients were matched with a control group of 100 healthy individuals. birth weight ≥ 4kg was de...

Diabetes mellitus is a group of metabolic disorders characterised by inadequate insulin production or response, leading to alteration of glucose metabolism. The two main forms of diabetes mellitus are type 1 and type 2. Type 1 diabetes mellitus involves insulin insufficiency arising from progressive immune-mediated destruction of pancreatic β-islet cells. Type 2 diabetes mellitus involves end-o...

The defining feature of diabetes mellitus is the presence of hyperglycemia. The most common forms of diabetes mellitus are type 1 diabetes mellitus, in which an absolute deficiency of insulin ensues consequent to pancreatic beta cell destruction, and type 2 diabetes mellitus, in which insulin resistance may lead to hyperglycemia. Obesity is an important risk factor for type 2 diabetes mellitus,...

BACKGROUND Diabetes mellitus and depression are highly prevalent conditions throughout the world and have significant impact on health outcomes. It has been estimated that diabetes mellitus type 2 affects about 246 million people in the world; nevertheless, incidence varies among countries. There is evidence that depression is associated with a poor metabolic control in patients with type 2 dia...

Diabetes mellitus and depression are highly prevalent conditions Background throughout the world and have significant impact on health outcomes. It has been estimated that diabetes mellitus type 2 affects about 246 million people in the world; nevertheless, incidence varies among countries. There is evidence that depression is associated with a poor metabolic control in patients with type 2 dia...