In this proof-of-concept study, gold nanoparticles (AuNPs) were immobilized on glassy carbon electrode (GCE) surfaces using a surface-anchored diazonium salt of 4-aminothiophenol (GCE-Ph-S-AuNPs). X-ray photoelectron spectroscopy (XPS) studies confirmed the attachment AuNPs via 4-thiophenol onto surface modified electrode. Differential pulse voltammetry (DPV) was performed for simultaneous dete...

In this paper, a micro-fluidic optimized process for the continuous flow synthesis of azo compounds is presented. The continuous flow synthesis of Sudan II azo dye was used as a model reaction for the study. At found optimal azo coupling reaction temperature and pH an investigation of the optimum flow rates of the reactants for the diazotization and azo coupling reactions in Little Things Facto...

Arene diazonium tetrafluoroborates can be synthesized from aromatic acetamides via a sequence of deacetylation, diazotation and precipitation, induced by anion exchange. The reaction is conducted as a convenient one-flask transformation with consecutive addition of the appropriate reagents. Exchange of solvents or removal of byproducts prior to isolation of the product is not required. The aren...

Block copolymer nanolithography has been extended to the nanopatterning of organic functionalities on pyrolyzed photoresist carbon films (PPFs) via diazonium chemistry, using PS-b-P4VP as the template.

Despite the fact that it was put on market more than 60 years ago, hydrochlorothiazide (HCT) is still one of most important antihypertensive drugs. Due to its chemical structure, which contains secondary aryl-alkyl-amino moiety, vulnerable formation N-nitrosamine drug substance-related impurity (NDSRI) N-nitroso-hydrochlorothiazide (NO-HCT). In our study, we reveal NO-HCT degrades rapidly at pH...

The title compound is a new pyrazolone derivative which was synthesized starting from p-sulphophenyl-3-methyl-5-pyrazolone (1) by nitrosation at low temperature to afford the corresponding p-sulphophenyl-3-methyl-4-nitroso-5-pyrazolone can exist both in nitroso (2a) and oxime tautomeric forms (2b). Reduction of latter using zinc with hydrochloric acid furnished 4-amino-p-sulphophenyl-3-methyl-5...

The formation of gratings on gold nanoprisms arrays by plasmon-mediated reduction a diazonium salt is investigated. Nanosphere lithography (NSL) used to produce large surfaces that are effective at reducing salts producing hot electrons through excitation localized surface plasmon resonances (LSPRs). Using single beam irradiation, we report here the periodic structures formed from and follow NS...