Semi-Volatile Organic Compounds (SVOCs) are commonly present in dwellings and several are suspected of having effects on male reproductive function mediated by an endocrine disruption mode of action. To improve knowledge of the health impact of these compounds, cumulative toxicity indicators are needed. This work derives Benchmark Doses (BMD) and Relative Potency Factors (RPF) for SVOCs acting ...

A new green alternative vortex-assisted dispersive liquid–liquid microextraction method based on a natural hydrophobic deep eutectic solvent was developed for the extraction of 14 phthalic acid esters and one adipate in cold infusions tonic waters. Analyses were carried out using ultra-performance liquid chromatography coupled to tandem mass spectrometry. Different mixtures monoterpene thymol (...

In this study, it was aimed to qualitatively determine Bisphenol A and dibutyl phthalate residues in carboy, pet bottled tap waters used as drinking water Kayseri-Türkiye. Being an additive the production of many products plastics frequently daily life, BPA phthalates are associated with a variety health issues environmental problems. Within scope total 20 samples (9 pet, 7 carboy 4 water) were...

IMPORTANCE Preterm birth is a leading cause of neonatal mortality, with a variety of contributing causes and risk factors. Environmental exposures represent a group of understudied, but potentially important, factors. Phthalate diesters are used extensively in a variety of consumer products worldwide. Consequently, exposure in pregnant women is highly prevalent. OBJECTIVE To assess the relati...

BACKGROUND Contradictory results exist regarding the importance of early-life exposure to phthalates for development of childhood eczema. OBJECTIVES We evaluated the association between maternal urinary concentrations of phthalate metabolites between the 24th and 28th week of gestation and occurrence of eczema in their sons up to 5 y of age, according to allergic sensitization as assessed by ...

Phthalate exposure is widespread among pregnant women but whether it is related to fetal growth and birth weight remains to be determined. We examined whether first trimester prenatal phthalate exposure was associated with birth weight in a pregnancy cohort study. We recruited first trimester pregnant women from 2010-2012 from four centers and analyzed mother/infant dyads who had complete urina...

Food contact materials (FCM) are any type of item intended to come into contact with foods and thus represent a potential source for human exposure to chemicals. Regarding FCMs made of paper and board, information pertaining to their chemical constituents and the potential impacts on human health remains scarce, which hampers safety evaluation. We describe an effect-directed strategy to identif...

The widespread use of plastic bags in routine blood bank procedures has been attended by concern about the accumulation of substances from the plastic containers in the blood products and the biologic effects of these substances (1-11). Most poly(vinyl chloride) plastic bags contain di-2-ethylhexyl phthalate (DEHP) to make them pliable enough to prevent breakage (2, 5). This material has been s...

Phthalates are organic contaminants that used as plasticizers in many plastic food packaging materials. Because of their lipophilic character, oils the primary source human exposure to phthalates. In this study, presence five phthalate esters; diethylhexyl (DEHP), dibutyl (DBP), butyl benzyl (BBP), diisononyl (DINP) and diisodecyl (DIDP) olive flavored with different materials marketed Turkey 2...