Studies were performed to determine the unknown status of PKC and RhoA/ROCK in the phorbol 12,13-dibutyrate (PDBu)-stimulated state in the human internal anal sphincter (IAS) smooth muscle cells (SMCs). We determined the effects of PDBu (10(-7) M), the PKC activator, on PKCα and RhoA and ROCK II translocation in the human IAS SMCs. We used immunocytochemistry and fluorescence microcopy in the b...

An automated drilling system requires a real-time evaluation of the bit during to optimize operation and determine when stop switch bits. Furthermore, in dynamic modeling drill strings, it is necessary take into account interactions between bits rock. To address this challenge, hybrid approach that combines physics-based models with data analytics has been developed handle downhole measurements...

Sorting is a useful predictor for permeability. We show how to invert seismic data for a permeable rock sorting parameter by incorporating a probabilistic rock-physics model with floating grains into a Bayesian seismic inversion code that operates directly on rock-physics variables. The Bayesian prior embeds the coupling between elastic properties, porosity, and the floating-grain sorting param...

17 18 Over the last decade, terrestrial laser scanning and digital terrestrial photogrammetry techniques have 19 been increasingly used in the geometrical characterization of rock slopes. These techniques provide 20 innovative remote sensing tools which overcome the frequent problem of rock slope inaccessibility. 21 Comprehensive datasets characterizing the structural geological setting and geo...

The aim of the paper is to develop a fully 3D simulation technique for rockfall dynamics taking rock shape into account and using the state-of-the-art methods of multibody dynamics and nonsmooth contact dynamics. The rockfall simulation technique is based on the nonsmooth contact dynamics method with hard contact laws. The rock is modeled as an arbitrary convex polyhedron and the terrain model ...

Abstract Digital rock is an emerging area of physics, which involves scanning reservoir rocks using X-ray micro computed tomography (XCT) scanners and it for various petrophysical computations evaluations. The acquired CT projections are used to reconstruct the attenuation maps rock. image reconstruction problem can be solved by utilization analytical (such as Feldkamp–Davis–Kress (FDK) algorit...

A technique to digitally document and thereby permanently preserve prehistoric rock art has been developed. Laser scanning and texture mapping from digital images were used. Methods involving texture mapping require the exact relationships between the image and geometrical sensors. For geological structures, such as caves, the distinctive features required for registering the texture with the g...

We present a suite of extensions for ARCVIEW GISTM (ESRI) that allows to map the spatial distribution of first-order mechanical slope-properties in hard rock terrain, e.g. for large slope areas like water reservoir slopes. Besides digital elevation data, this expert-system includes regional continuous grid-based data on geological structures that might act as potential sliding or cutoff planes ...