BACKGROUND Virchow's triad in cardiovascular disease comprises blood viscosity, plasma D-dimer and homocysteine as indices of three associated but separate vascular phenomena. AIMS This work investigates prevalence of hyperviscosity in hyperhomocysteinaemia and positive D-dimer; and differences or similarities in stasis status among sub-populations of hyperhomocysteinaemia vs. normohomocystei...

There is still a considerable uncertainty concerning D-dimer cut-off values used in exclusion of venous thromboembolic (venous thromboembolism, VTE) disease, especially among the elderly patients. The objectives were to compare five different D-dimer reagents in the daily practice of an emergency department and to test retrospectively the performances of an age-adjusted cut-off. A total of 473 ...

We study the resonant effects produced when a Feshbach dimer crosses a scattering continuum band of atoms in an optical lattice. We numerically obtain the exact spectrum of two particles in a one-dimensional lattice and develop an effective atom-dimer Hamiltonian that accurately captures resonant effects. The lattice-induced resonances lead to the formation of bound states simultaneously above ...

The strong short-range repulsion, characteristic to realistic interatomic potentials, complicates the description of weakly-bound few-body systems such as those \He atoms. present work proposes an approach for solving this problem and applies it a system four ${}^4\mathrm{He}$ potential is gradually softened that rigorous four-body equations bound scattering tates can be accurately solved in mo...

This paper presents a computational and theoretical investigation of the vacuum mechanosynthesis of diamond on the clean C(110) surface from carbon dimer (C2) precursors. Part I provided a detailed atomic picture of the dimer-mediated surface chemistry during the gas-phase growth of dehydrogenated diamond C(110) from C2 plasmas, deducing some of the many possible stabilized defects that can be ...

Structural and mechanistic studies of the lithium diisopropylamide (LDA)-mediated anionic Fries rearrangements of aryl carbamates are described. Substituents at the meta position of the arene (H, OMe, F) and the dialkylamino moiety of the carbamate (Me(2)N, Et(2)N, and i-Pr(2)N) markedly influence the relative rates of ortholithiation and subsequent Fries rearrangement. Structural studies using...

Formin proteins participate in a wide range of cytoskeletal processes in all eukaryotes. The defining feature of formins is a highly conserved approximately 400 residue region, the Formin Homology-2 (FH2) domain, which has recently been found to nucleate actin filaments. Here we report crystal structures of the S. cerevesiae Bni1p FH2 domain. The mostly alpha-helical FH2 domain forms a unique "...