We suggest four new benzene dimers, (C(6)H(6))(2), all featuring one or more cyclohexadiene rings trans-fused to 4- or 6-membered rings. These hypothetical dimers are 50-99 kcal/mol less stable than two benzenes, but have computed activation energies to fragmentation ≥27 kcal/mol. A thorough search of potential escape routes was undertaken, through cyclobutane ring cleavage to 12-annulenes, sig...

Generalizing results of Temperley [11], Brooks, Smith, Stone and Tutte [1] and others [10, 7] we describe a natural equivalence between three planar objects: weighted bipartite planar graphs; planar Markov chains; and tilings with convex polygons. This equivalence provides a measure-preserving bijection between dimer coverings of a weighted bipartite planar graph and spanning trees of the corre...

Background: Severe coronavirus disease 2019 (COVID-19) courses are characterized by immuno-inflammatory, thrombotic, and parenchymal alterations. Prediction of individual COVID-19 to guide targeted prevention remains challenging. We hypothesized that a distinct serologic signature precedes surges IL-6/D-dimers in severely affected patients. Methods: performed longitudinal plasma profiling, incl...

A hyperimmune rabbit antiserum to ultraviolet-irradiated DNA was observed to contain two activities directed against irradiated DNA. Radioimmunoassay studies demonstrated that both antigenic determinants were pyrimidine dimers as evidenced by the reduction in antibody binding to enzymatically photoreactivated irradiated DNA. Enzymatic photoreactivation specifically monomerizes pyrimidine dimers...