OBJECTIVE Policy and law encouraging individuals to document their wishes for life-sustaining medical treatment in advance of serious illness assumes that these wishes are unaffected by changes in health condition. To test this assumption, the authors examine the life-sustaining treatment preferences of a sample of elderly adults prior to, soon after, and several months after a hospitalization ...

Localized changes in oxygen consumption related to increased neural activity can result in a small and transient "initial dip" of the blood oxygenation level-dependent (BOLD) signal used in functional magnetic resonance imaging (fMRI). The initial dip has been of great interest to the fMRI community because it may provide a more accurate and localized measure of neural activity than the convent...

Tumor cells rely upon membrane pliancy to escape primary lesions and invade secondary metastatic sites. This process relies upon localized assembly and disassembly cycles of F-actin that support and underlie the plasma membrane. Dynamic actin generates both spear-like and bleb structures respectively characterizing mesenchymal and amoeboid motility programs utilized by metastatic cells in three...

The Internet Distance Map Service (IDMaps) [3] provides distance estimates between any pair of hosts connected to the Internet. The IDMaps system comprises two component types: Tracers that measure distances between IP address prefixes, and Servers that collect measurement results and answer distance queries. The Distance Information Protocol (DIP) is used for Tracers to report measured distanc...

The synthesis and spectroscopic characterisation of six bis(5-X-pyridine-2-yl)isophthalamides (X = H, F, Br, Cl, I, NO2) are reported, together with five crystal structure analyses (for X F to I). isophthalamides span a range conformations as syn/anti (H-DIP; I-DIP), anti/anti- (F-DIP; Br-DIP) both present in ratio 2:1 Cl-DIP. essentially isostructural F-DIP Br-DIP molecules (using strong amide...

CP Tuc (AX J2315–592) shows a dip in X-rays which lasts for approximately half the binary orbit and is deeper in soft X-rays compared with hard X-rays. It has been proposed that this dip is due to the accretion stream obscuring the accretion region from view. If CP Tuc was a polar, as has been suggested, then the length of such a dip would make it unique amongst polars since in those polars in ...

We report a rare case of desquamative interstitial pneumonia (DIP) with diffuse alveolar haemorrhage (DAH). A 56-year-old man diagnosed with DIP by surgical lung biopsy 2 years ago was admitted to our hospital because of severe acute respiratory failure. The DIP had progressed despite smoking cessation. On admission, the patient appeared extremely ill, and physical examination revealed respirat...

D esquamative interstitial pneumonitis ( DIP) is an inflammatory process in the lung characterized histologically by massive accumulation of intra-alveolar mononuclear cells, predominantly alveolar macrophages ( PAMs ) , without necrosis, fibrin exudates, hyaline membranes, or extensive fibrosis.1’2 Whether DIP is a distinct clinicopathologic entity or is merely part of a spectrum of fibrosing ...

Objectives—To derive a method for retrospectively estimating cumulative exposure to organophosphate (OP) pesticides among a cross section of United Kingdom sheep dippers, as part of a wider epidemiological study of neurological abnormality within this group of workers. Methods—A hygiene study of dipping sessions at 20 farms using diazinon based dips was carried out by two experienced occupation...