Abstract Innovative selling channels have brought about opportunities as well challenges for upstream manufacturers. The past few years witnessed both the success and failure of manufacturers with different channel strategies. To explore rationale strategies in various contexts, we develop a model to analyze manufacturer's selection decision among three strategies, i.e., direct-channel strategy...

The human Kv1.5 potassium channel (hKv1.5) contains proline-rich sequences identical to those that bind to Src homology 3 (SH3) domains. Direct association of the Src tyrosine kinase with cloned hKv1.5 and native hKv1.5 in human myocardium was observed. This interaction was mediated by the proline-rich motif of hKv1.5 and the SH3 domain of Src. Furthermore, hKv1.5 was tyrosine phosphorylated, a...

Today's multichannel, multimedia retail marketing environment presents a number of brand management challenges. From a micro perspective, marketers must manage each individual channel and communication option to maximize their direct sales and brand equity effects, as well as any indirect brand equity effects from being associated with a particular channel or communication option. From a macro ...

Abstract In this paper, a zero-delay channel estimation scheme based on both pilot and traffic channels is proposed for next generation direct sequence codedivision multiple-access (DS/CDMA) systems. This scheme has no channel estimation delay, and is found to perform significantly better than a zero-delay channel estimation scheme based on only pilot channel. The elimination of channel estimat...

in biaxially strained p-mosfet with si channel, formation of a parasitic parallel channel due to misalignment of energy bands degrades device performance by increasing off-state current. in this paper a new approach has been introduced to eliminate this parasitic channel by increasing the dopant concentration of virtual substrate up to . using simulation the impact of this method on the parasit...

In 2007 over $30 Billion in US retail sales were driven by over 15 million US direct sales distributors selling everything from cosmetics, household goods, nutrition, life insurance and mortgages. (Direct Selling Association). In the direct selling industry, prior to the Internet, direct sales presentations relied on a direct selling distributor traveling to the prospect’s home to make a presen...

zinc is a substance that regulates neural excitability by binding whit sodium channel and potassium channel. the efficiency of free zinc ion, make down the neural survival rate, reduced the peak amplitude of na+ and make depolarization na channel, increased the peak amplitude of transition outward k+ currents and delayed rectifier. also it is an effective blocker of one subtype of tetrodoxine (...

A key challenge in censorship-resistant web browsing is being able to direct legitimate users to redirection proxies while preventing censors, posing as insiders, from discovering their addresses and blocking them. We propose a new framework for censorship-resistant web browsing called CensorSpoofer that addresses this challenge by exploiting the asymmetric nature of web browsing traffic and ma...

In neurons, entry of extracellular calcium (Ca(2+)) into synaptic terminals through Cav2.1 (P/Q-type) Ca(2+) channels is the driving force for exocytosis of neurotransmitter-containing synaptic vesicles. This class of Ca(2+) channel is, therefore, pivotal during normal neurotransmission in higher organisms. In response to channel opening and Ca(2+) influx, specific Ca(2+)-binding proteins assoc...