negative impact of delays on customer service level by keeping redundant inventory or safety stock. Although safety stock protects companies from disruptions or delays, this comes at a cost because higher inventory levels tie up working capital and increase inventory management costs, such as warehousing and damage rates. In addition, the higher inventory level increases the risks associated wi...

Malformations of cortical development (MCD) result from disruptions in the complex process of the human brain cortex formation and are highly associated to severe epilepsy, neurodevelopmental delay and motor dysfunction. Nowadays, magnetic resonance imaging (MRI) is the cornerstone of the work-up of patients with epilepsy and modern advanced imaging techniques have improved not only our ability...

Tourette syndrome (TS) is a neurodevelopmental disability characterised by a cognitive profile of executive function deficits, particularly relating to inhibitory control. There is much evidence that TS is likely to occur comorbidly with other disorders and that this may exacerbate the presence o f cognitive disruptions. Attention Deficit Hyperactivity Disorder (ADHD) is one of the neurodevelop...

Disruptions in end-to-end path connectivity, which last longer than one retransmission timeout, cause suboptimal TCP performance. The reason for this performance degradation is that TCP interprets segment loss induced by long connectivity disruptions as a sign of congestion, resulting in repeated retransmission timer backoffs. This, in turn, leads to a delayed detection of the re-establishment ...

In this paper we consider a generalization of the p-center problem called the r-all-neighbor p-center problem (RANPCP). The objective of the RANPCP is to minimize the maximum distance from a demand point to its rth-closest located facility. The RANPCP is applicable to facility location with disruptions because it considers the maximum transportation distance after (r − 1) facilities are disrupt...

A primary function of air traffic flow management is to strategically shape traffic demand to match capacities (e.g., airport arrival/departure rate limits and Sector capacities), without imposing excessive delay. In the current United States National Airspace System (NAS), the disruptions modulating capacities and hence traffic management are predominantly weather events, including convection,...

Critical Infrastructures’ disruptions may result in crises of unacceptable outcomes in modern societies. Thus, it is important to develop models that allow describing CIs’ disruptions and their propagation characteristics. CI disruptions depend on both the type of the threat and on the nature of the CIs’ mutual dependencies. A model describing the cascade of disruptions should, then, be able to...

Purpose:The purpose of this secondary analysis was to explore the associations between the frequency of hot flashes and sleep disruptions experienced by post menopausal women with the diagnosis of breast cancer and received acupuncture treatments for hot flashes. Data Sources: Data were gathered for this secondary analysis from 47 African-American, Hispanic, and Caucasian women experiencing hot...

Disruptions in end-to-end path connectivity, which last longer than one retransmission timeout, cause suboptimal TCP performance. The reason for this performance degradation is that TCP interprets segment loss induced by long connectivity disruptions as a sign of congestion, resulting in repeated retransmission timer backoffs. This, in turn, leads to a delayed detection of the re-establishment ...

INTRODUCTION Subjective cognitive decline (SCD) refers to an at-risk state of Alzheimer's disease and subtle cognitive deficits that have been observed in this condition. Currently, it is unknown whether complex cognitive processes relevant to everyday life, such as future-oriented choice behavior, are also altered in SCD. METHODS Twenty SCD participants and 24 control (CO) participants took ...