OBJECTIVE MiR-183 acts as an oncomiR and is usually upregulated in hepatocellular cancer (HCC). This study aims to study the association between miR-183 dysregulation and multi-drug resistance (MDR). Also, how it is dysregulated in HCC cells was investigated. MATERIALS AND METHODS The association between miR-183 and HIF-1α in HCC cell line BEL-7402 and the multidrug-resistant variant BEL-7402...

The negative impact of urbanization on biodiversity can be buffered by blue (e.g., rivers, ponds) and green parks, forests) spaces. However, to prevent loss reduce the risk local extinctions, spaces need connected corridors, so that organisms may disperse between sites. Landscape connectivity affects community composition metacommunity dynamics facilitating dispersal. goal this study was test r...

The aim of the current study was to investigate the potential role of microRNA-183-5p (miR-183-5p) in the proliferation, invasion and metastasis of pancreatic cancer, and to identify promising target genes of oncogenic miR-183-5p. Western blotting and quantitative polymerase chain reaction (qPCR) were used to investigate whether these oncogenic microRNAs may be useful as biomarkers in pancreati...

As a highly aggressive malignant disease, the prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) is poor. Yet, the mechanisms underlying the progression of PDAC remain unclear. MicroRNAs (miRNAs) may be involved in various human cancers as cancer suppressors or oncogenes. MicroRNA-183 (miR-183) was recently reported to be dysregulated in various types of cancer and to play an im...

Disperse dye inks are used in the inkjet textile printing of polyester fabrics. We aimed at developing a black disperse dye ink consisting of yellow, magenta, and cyan dyes that met the exacting requirements of safety, image durability, and storage stability. One difficulty we met was dye particles tending to aggregate/agglomerate, leading to sedimentation and the threat of head clogging and/or...

miR-183, a member of an evolutionarily conserved miRNA cluster (miR-96, miR-182, and miR-183), has been demonstrated to act as both a tumor suppressor and oncogene in various type of human cancer. However, the biological role of miR-183 in gastric cancer (GC) still remains unclear. In the present study, miR-183 expression was significantly decreased in gastric cancer tissues compared with its' ...