Effect of temperature on hold-up volume, enantioselectivity and robustness of a novel doubly tethered diproline chiral stationary phase (CSP1) was studied. In-column end-capping of residual silanol was utilized as a tool to exhibit in situ change of CSP1. The hold-up volume marker, 1,3,5-tri-tert-butylbenzene, was observed to be weakly retained (<1 s ) on a 5 cm×4.6 mm chiral column, and its re...

        The purpose of this study was to prepare and characterize nimodipine loaded microspheres using ethyl cellulose (EC) as a carrier polymer through an emulsion solvent evaporation method. These evaluations characterized the pattern of drug release from prepared microspheres. Nimodipin loaded microspheres were prepared using an emulsification solvent evaporation method. The effect of proces...

in this study, liquid-liquid extraction process in a kuhni extraction column was modeled and simulated. a non-equilibrium dynamic model was developed for modeling liquid-liquid extraction processes based on a rate-based model. the model equations are inclusive of partial and ordinary differential equations which were discretized in column height direction. the population balance model was used ...

In this research mass transfer coefficient under jetting regime in different directions (from dispersed to continuous and continuous to dispersed phase) has been studied using an experimental setup. n-Butanol-succinic acid-water with low interfacial tension has been selected as experimental chemical system. The effects of various parameters such as jet velocity, nozzle diameter and the heig...

We consider an emulsion whose droplets contain a trapped species (insoluble in the continuous phase), and study the emulsion’s stability against coarsening via Lifshitz–Slyozov dynamics (Ostwald Ripening). Extending an earlier treatment by Kabalnov et al(Colloids and Surfaces, 24 (1987), 19-32), we derive a general condition on the mean initial droplet volume which ensures stability, even when ...

Microfluidic schemes for forming uniform aqueous microdroplets usually rely on contacting the aqueous liquid (dispersed phase) with an immiscible oil (continuous phase). Here, we demonstrate that the oil can be substituted with gas (nitrogen or air) while still retaining the ability to generate discrete and uniform aqueous droplets. Our device is a capillary co-flow system, with the inner flow ...

Food-grade microemulsions containing oleic acid, ethanol, Tween 20, and water were formulated as a carrier system for tea seed oil (Camellia oleifera Abel.). The effect of ethanol on the phase behavior of the microemulsion system was clearly reflected in pseudo-ternary diagrams. The solubilization capacity and solubilization efficiency of tea seed oil dispersions were measured along the dilutio...