Legionella pneumophila is the most common cause of legionellosis and is one of the organisms causing atypical pneumonia. We report the presentation of disseminated intravascular coagulation (DIC) and skin rash in a single case of severe Legionella pneumonia. The unique clinical presentation of a diffuse rash diagnosed as purpura fulminans and the unpredictable variations encountered during the ...

The management of chronic disseminated intravascular coagulation (DIC) caused by aortic dissection has not yet been established. Even in cases where surgical correction is performed, therapeutic control of systemic hemorrhaging is still required. We herein report the successful treatment of a case of aortic dissection with a patent false lumen using tranexamic acid for acute exacerbation of chr...

Neonatal skin necrosis in the context of a congenital homozygous protein C deficiency is rare inherited autosomal recessive disorder, it characterized by rapidly extensive necrotic patches occurring few hours after birth newborn who doesnt present any hemodynamic disorder. The diagnosis based on assay activity which collapsed or even undetectable. Early and replacement therapy are mainstays man...

Patients with acute myelogenous leukemia complicate with disseminated intravascular coagulation (DIC), not only at the time of the initially leukemia diagnosis, but also during induction chemotherapy. In Japan, recently, a recombinant human soluble thrombomodulin alpha (Recomodulin) has been introduced as a new type of anti-DIC agent for clinical use in patients with hematological cancer or inf...

Septic adrenal hemorrhage is classically caused by meningococcemia. An autopsied case is presented of a 45-year-old man with adrenal hemorrhage due to Klebsiella oxytoca bacteremia following placement of a central venous catheter. He died 5 hours after developing disseminated intravascular coagulation (DIC). The bacterial entry site may have been the catheter. The cause of death was considered ...

Disseminated intravascular coagulation (DIC) is the most frequent coagulation disorder in patients with prostate cancer. However, renal involvement in DIC associated with prostate cancer has rarely been documented. Herein, we present a case of metastatic prostate cancer presenting with acute renal failure (RF) triggered by DIC. An 80 year old man with metastatic prostate cancer was treated with...

Introduction The term of macrophage activation syndrome (MAS) refers to a condition caused by excessive activation and expansion of T lymphocytes and macrophagic histiocytes that exhibit hemophagocytic activity. The expansion of these cells also leads to a massive systemic inflammatory response associated with pan cytopenia, liver dysfunction, and coagulopathy consistent by disseminated intrava...

The advancement of chemotherapy with antimicrobial agents to which gram-positive cocii are highly sensitive has brought with it a markede decline in severe odontogenic infections. However, if the primary treatment is inadequate or a patient is immunocompromised, odontogenic infections easily develop into serious conditions. This is the report of two cases of odontogenic infections which caused ...

Background: Disseminated intravascular coagulation (DIC) has a high prevalence in critically ill neonates. In suspicion of DIC based on abnormal parameter is common trigger to transfuse fresh frozen plasma (FFP), even absence bleeding. past years, use FFP increased and expanded include prophylactic neonates especially neonatal intensive care units (NICUs) as it contains several factors. Several...

We report the case of a 34 year old woman with acute respiratory distress syndrome (ARDS) and disseminated intravascular coagulation (DIC) due to methicillin-resistant Staphylococcus aureus (MRSA) sepsis with hyperimmunoglobulin E syndrome (HIES). Although chemotactic activity of neutrophils was impaired in this patient, neutrophils accumulated in the lungs as assessed by bronchoalveolar lavage...