نتایج جستجو برای: dissolution kinetics

تعداد نتایج: 116356  

2014
B. Kweto D. R. Groot E. Stassen J. Suthiram J. R. Zeevaart

The purpose of this study was to determine the kinetics of the dissolution of a uranium residue in ammonium carbonate media. The residue is generated in the production of medical isotopes. The effects of parameters, such as varying peroxide and carbonate concentrations, dissolution time as well as temperature on the extraction rate have been separately studied. Results indicate complete dissolu...

Journal: :Journal of clinical pharmacology 2008
Jian Wang Michael Weiss David Z D'Argenio

Because conventional absorption models often fail to describe plasma concentration-time profiles following oral administration, empirical input functions such as the inverse Gaussian function have been successfully used. The purpose of this note is to extend this model by adding a first-order absorption process and to demonstrate the application of population analysis using maximum likelihood e...

Journal: :Journal of lipid research 1984
N Rajagopalan S Lindenbaum

The kinetics of dissolution of dispersions of egg phosphatidylcholine (lecithin) by bile salts was studied by observing the decrease in turbidity as mixed micelles of lecithin and bile salt were formed. The rate of dissolution of lecithin corresponding to the formation of mixed micelles was studied in the presence of dihydroxy bile salts, sodium deoxycholate, sodium chenodeoxycholate, sodium ur...

Journal: :Physical review. E, Statistical, nonlinear, and soft matter physics 2010
S D C Walsh M O Saar

This paper describes a method for implementing surface reaction kinetics in lattice Boltzmann simulations. The interpolated boundary conditions are capable of simulating surface reactions and dissolution at both stationary and moving solid-fluid and fluid-fluid interfaces. Results obtained with the boundary conditions are compared to analytical solutions for first-order and constant-flux kineti...

1997
Julie V. Macpherson Patrick R. Unwin Andrew C. Hillier Allen J. Bard

The kinetics and mechanism controlling dissolution from the (100) cleavage face of potassium bromide single crystals in acetonitrile solutions have been identified using a novel integrated electrochemical/AFM probe and a scanning electrochemical microscope (SECM). With both techniques, dissolution is induced by perturbing the dynamic dissolution/growth equilibrium at the crystal/solution interf...

2016
Amjad Khan Zafar Iqbal Abad Khan Muhammad Akhlaq Mughal Abbas Khan Zia Ullah Ismail Khan

Drug release from polymeric matrix systems is the rate-limiting step for drug bioavailability and is determined by drug solubility; most drugs show pH-dependent solubility. Polymeric matrices remain in the gastrointestinal tract for a longer period of time and are exposed to environments of varying pH, which can adversely affect drug release. In the present study, the pH-independent drug releas...

2009
A. Mesnukul K. Yodkhum T. Phaechamud

The purpose of this study is to fabricate the polyethylene glycol matrix tablet by mold technique. Indomethacin and hydroxypropylmethylcellulose were used as model drug and polymer, respectively, in PEG matrix system. The physical and drug release characteristics of developed matrix tablet were studied. This inert carrier system comprising 7:3 polyethylene glycol 4000: polyethylene glycol 400 c...

Journal: :Physical chemistry chemical physics : PCCP 2013
Yi Yang Yujia Min Young-Shin Jun

A quantitative description of how the bulk properties of aluminosilicates affect their dissolution kinetics is important in helping people understand the regulation of atmospheric CO2 concentration by silicate weathering and predict the fate and transport of geologically sequestered CO2 through brine-rock interactions. In this study, we employed a structure model based on the C1 space group to ...

2013
H. F. Aly M. M. Ali M. H. Taha

The dissolution kinetics of the Abu-Tartur phosphate rock using dilute hydrochloric acid has been investigated. The influence of acid concentration, liquid/solid ratio, particle size and temperature was studied to explore the dissolution kinetics of phosphate rock. It was found that the leaching rate increases with increasing the acid concentration, liquid/solid ratio, temperature and decreases...

Journal: :J. Comput. Physics 2007
Etelvina Javierre Cornelis Vuik Fred J. Vermolen A. Segal

A sharp interface method is proposed for the dissolution of stoichiometric particles in multi-component alloys occurring during the heat treatments of as-cast aluminium alloys prior to hot extrusion. In the mathematical model, a number of non-linearly coupled diffusion equations are given to determine the position of the particle interface and the interfacial concentrations. A level set method ...

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