New methods of limb lengthening are being adopted in the hope of overcoming the poor osteogenic responses characteristic of distraction. Delay between the osteotomy and starting distraction is said to be important but there is little experimental evidence. We have compared immediate with delayed distraction in the rabbit tibia and shown that delay is an important factor in promoting osteogenesi...

Alveolar distraction is being used increasingly for alveolar bone reconstruction in patients with severe mandibular defects. When there has been total loss of alveolar bone, distraction of the mandibular basal bone is necessary. Distraction osteogenesis is considerably more challenging in mandibular basal bone than in alveolar bone. The low level of the cut increases the technical difficulty an...

UNLABELLED Since the approval of parathyroid hormone (PTH) as treatment for osteoporosis, PTH has increasingly been investigated for bone repair and regeneration. The aim of the study was to investigate the effects of intermittent PTH treatment on the microstructure of regenerated mineralizing tissue after distraction osteogenesis in rabbits. After tibial mid-diaphyseal osteotomy the callus was...

INTRODUCTION: Traditional frontoorbital advancement with a supraorbital bar is the standard technique for correcting coronal craniosynostosis. However, several reports indicate that cranioplasty using distraction osteogenesis can be an alternative. To maximize the advantages of distraction, preservation of the dura attachment to the frontal bone appears to be important. Therefore, we designed a...

After resection and autogenous bone grafting in infancy and childhood, hypotrophy of the concerned jaw can often be observed. A 6-year-old male patient with osteogenic sarcoma was treated with partial resection of the mandible from the left first molar to the right first premolar. The aim was to rehabilitate the patient functionally and esthetically as he grew. At the age of 16, after the place...

Computerized surgical planning protocols for distraction osteogenesis are still in their rudimentary phase. The authors have developed a system to plan distraction osteogenesis in craniofacial and maxillofacial surgery that uses three-dimensional computed tomography scans and computer simulation in a virtual reality environment. This involves the creation of a three-dimensional bone model of th...

Free vascularized fibular flap is considered the treatment of choice in mandibular reconstruction for extensive bone defects (over 6 centimeters) resulting from trauma, infections or tumor resections. But, when the reconstruction involves a dentate mandible, the fibula has the limit as it does not offer sufficient bone height to restore the alveolar arch up to the occlusal plane. Therefore, the...

Bone is one of the most dynamic tissues in the human body that can heal following injury without leaving a scar. However, in instances of extensive bone loss, this intrinsic capacity of bone to heal may not be sufficient and external intervention becomes necessary. Several techniques are available to address this problem, including autogenous bone grafts and allografts. However, all these techn...

Objective: The current study was aimed at introducing a novel method to manage the mangled extremity by upper limb reconstruction using distraction osteogenesis. Methods: A 25-year-old man was admitted to our hospital after a severe mangled injury, his right forearm bones and the surrounding soft tissues were compromised. After initial debridement, the infection of his right forearm recurred. U...

We performed an orthodontic treatment combined with mandibular distraction osteogenesis in a 15-year-old patient who wanted a correction of a chin deficiency and a protruding upper lip. The patient had an Angle Class II division 1 malocclusion with mandibular retrusion, a low mandibular plane angle, and scissors bite. First, a quad-helix appliance was applied to the mandibular dentition to corr...