نتایج جستجو برای: dn
تعداد نتایج: 7049 فیلتر نتایج به سال:
Diabetic nephropathy (DN) remains an unmet medical challenge as its prevalence is projected to continue to increase and specific medicines for treatment remain undeveloped. Activation of the immune system, in particular T-cells, is emerging as a possible mechanism underlying DN disease progression in humans and animal models. We hypothesized that inhibition of T-cell activation will ameliorate ...
The aim of the study was to find the correlation between CRP and chemerin in development of DN. We choose 90 type-2 diabetic patients between February 2010 and February 2013, who were then divided into DN group and healthy control group. The results of BP showed that there is no difference in SBP and DBP of patients in the three groups. HDL-C of patients in diabetic group and DN group is lower ...
BACKGROUND Diabetic nephropathy (DN) is a common complication of diabetes, caused by diabetic microvascular lesions. The pathogenesis of DN is complicated, involving genetics, physics, chemistry, and environmental factors. Chemerin is a fat cell factor that participates in regulating inflammation. Vascular endothelial growth factor (VEGF) promotes vascular endothelial cell proliferation, differ...
In this article, we obtain two sets of results. The first set results are for the case bi-disc while second describe in part, which these carry over to general poly-disc. A classification irreducible hermitian holomorphic vector bundles D2, homogeneous with respect Möb×Möb, is obtained assuming that associated representations multiplicity-free. Among ones give rise an operator Cowen-Douglas cla...
The ratio of divergence at nonsynonymous and synonymous sites, dN/dS, is a widely used measure in evolutionary genetic studies to investigate the extent to which selection modulates gene sequence evolution. Originally tailored to codon sequences of distantly related lineages, dN/dS represents the ratio of fixed nonsynonymous to synonymous differences. The impact of ancestral and lineage-specifi...
OBJECTIVE To investigate potential drugs for diabetic nephropathy (DN) using whole-genome expression profiles and the Connectivity Map (CMAP). METHODOLOGY Eighteen Chinese Han DN patients and six normal controls were included in this study. Whole-genome expression profiles of microdissected glomeruli were measured using the Affymetrix human U133 plus 2.0 chip. Differentially expressed genes (...
Recent studies have demonstrated that in peripheral lymphoid tissues of normal mice and healthy humans, 1% to 5% of alphabeta T-cell receptor-positive (TCR(+)) T cells are CD4(-)CD8(-) (double-negative [DN]) T cells, capable of down-regulating immune responses. However, the origin and developmental pathway of DN T cells is still not clear. In this study, by monitoring CD4 expression during T-ce...
ion Let τ = λx.σ. By the induction hypothesis, σ defines a function of its free variables. Let those free variables be of types D0, . . . ,Dn where Dn is the type of x. Then σ defines an approximable function g : D0 × . . .×Dn → D′ where D′ is the type of σ. Using Theorem 3.12, the function curry(g) : D0 × . . .×Dn−1 → (Dn → D′) yields an approximable function, but this is just the function def...
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