DNA methylation is emerging as an attractive marker providing investigative leads to solve crimes in forensic genetics. The identification of body fluids that utilizes tissue-specific DNA methylation can contribute to solving crimes by predicting activity related to the evidence material. The age estimation based on DNA methylation is expected to reduce the number of potential suspects, when th...

The article discusses the relevance of determining DNA double-strand breaks (DSBs) using analysis γ-H2AX foci as a marker instability in various conditions. issues formation DSBs and peculiarities their detection tissues are highlighted. Changes intensity during use radiological diagnostic methods, stress, increased physical exertion, some oncological rheumatic diseases, well dynamics repair on...

Background: Over than eight tenant groups make up Kurdistan region of Iraq local populations. Overall majority the inhabitants are Muslim Kurds, followed by Yezidi Kurds. Alternative including Armenians, Assyrian, Chaldea Syriacs as well a little minority Arab and Turkmen individuals. Methods: A total 60 unrelated males from three population in Arabs, Soran Behdinan kurd were successfully analy...

Serving as a DNA molecular weight standard, the DNA ladder has been widely used in molecular biology applications. We developed a simple method for the preparation of a DNA marker, which involves designing primers to amplify 100- to 1000-bp DNA fragments using lambda DNA as a template for polymerase chain reaction, followed by extraction with phenol/chloroform, precipitation with ethanol and mi...

DNA methylation, an epigenetic mechanism is claimed to play essential roles in development, aging and disease over the past few decades. Cytosines (C) were known to exist in two functional states: unmethylated or methylated (5mC) in the mammalian genome for a very long time. However, the mechanisms controlling 5mC dynamics remain undefined. Recent studies of genomic DNA on human and mouse brain...

Genetic mapping with DNA markers has become an essential tool for revealing the genetic basis of both qualitative and quantitative traits in crop plants. DNA markers have special advantages over morphological traits in genetic analysis because they are normally polymorphic, have no pleiotropic or epistatic effects, employ non-destructive methods requiring very small amounts of plant materials a...

Simple sequence repeats (SSRs), also referred to as microsatellites, are highly variable tandem DNAs that are widely used as genetic markers. The increasing availability of whole-genome and transcript sequences provides information resources for SSR marker development. However, efficient software is required to efficiently identify and display SSR information along with other gene features at a...