An 8-year-old male Austrian Pinscher and a 14-year-old male Golden Retriever were presented for evaluation due to unexplainable high fructosamine values despite euglycemia and epistaxis in combination with polydipsia/polyuria, respectively. Blood analysis revealed severe hyperglobulinemia, hypoalbuminemia and markedly elevated fructosamine concentrations in both dogs. Multiple myeloma with IgA-...

BACKGROUND Immune system involvement is suggested as an underlying cause for Doberman hepatitis (DH) based on female predisposition, lymphocyte infiltration, abnormal hepatocyte expression of major histocompatibility complex class II antigens, and homozygosity for dog leukocyte antigen DRB1*00601. OBJECTIVE To measure serum antinuclear antibodies (ANA) and serum antihistone antibodies (AHA) i...

This study presents a case of a canine thymolipoma, which is a rare, slow-growing, benign tumor of the thymus composed of mature adipose tissue and thymic tissue. A 9-year-old spayed, female miniature pinscher presented with chronic cough and dyspnoea. Radiology revealed pleural effusion and a mediastinal mass with a fatty appearance. The mass was attached to, and silhouetted, the adjacent peri...

tors. In contrast, prazosin, which blocks a1 noradrenerTwo recent papers have linked narcolepsy to dysfuncgic receptors, greatly exacerbates cataplexy in both tion of the newly discovered hypocretin (Hcrt) (orexin) dogs and humans. Cholinergic agonists and the cholinpeptide system. The paper by Lin et al. (1999 [previous esterase blocker physostigmine also exacerbate cataissue of Cell]) examine...