background: boron neutron capture therapy (bnct) is a radiotherapy that combines biological targeting and high linear energy transfer. a potential therapeutic approach for non-small cell lung cancer (nsclc) is considered. however, dose in lung tumor is not homogeneous, and it will reduce the effect of bnct treatment. in order to improve the dose distribution of bnct, the multi-field irradiation...

Purpose In this single-institution retrospective study, configuration analysis was performed to determine the optimal location and volume of hyaluronic acid gel spacer injection into rectovaginal or vesicovaginal septum for effective dose reduction (DR) organs at risk (OARs), rectum bladder. Methods materials 70 50 intracavitary brachytherapy treatment plans used only vaginal cylinders with spa...

PURPOSE To investigate the dosimetric advantage of intensity-modulated radiotherapy (IMRT) for whole ventricles (WV) in patients with a localized intracranial germinoma receiving induction chemotherapy. METHODS AND MATERIALS Data from 12 consecutive patients with localized intracranial germinomas who received induction chemotherapy and radiotherapy were used. Four-field coplanar three-dimensi...

BACKGROUND Patients with glioblastoma multiforme (GBM) require radiotherapy as part of definitive management. Our institution has adopted the use of volumetric arc therapy (VMAT) due to superior sparing of the adjacent organs at risk (OARs) compared to intensity modulated radiation therapy (IMRT). Here we report our clinical experience by analyzing target coverage and sparing of OARs for 90 cli...

The purpose of this study was to determine appropriate beam arrangement for volumetric-modulated arc therapy (VMAT)-based stereotactic body radiation therapy (SBRT) in the treatment of patients with centrally located lung tumors. Fifteen consecutive patients with centrally located lung tumors treated at our institution were enrolled. For each patient, three VMAT plans were generated using two c...

Discretization errors due to the digitization of computed tomography images and the calculation grid are a significant issue in radiation therapy. Such errors have been quantitatively reported for a fixed multifield intensity-modulated radiation therapy using traditional linear accelerators. The aim of this study is to quantify the influence of the calculation grid size on the dose distribution...

We treated prostate cancer patients with static 5-field intensity-modulated radiation therapy (IMRT) using linac 18-MV X-rays or tomotherapy with 6-MV X-rays. As X-ray energies differ, we hypothesized that 18-MV photon IMRT may be better for large patients and tomotherapy may be more suitable for small patients. Thus, we compared dose-volume parameters for the planning target volume (PTV) and o...

Introduction: In 3DCRT the number of therapeutic fields has dramatic impact on treatment results especially in stomach cancer. Traditionally, for radiotherapy of stomach cancer the therapeutic procedure was using two fields (AP- PA or AP Lateral with wedge) to achieve smooth and homogeneous dose distribution in tumor. But nowadays, adding lateral or oblique fields to aforement...

Purpose : This study aims to compare the dosimetric differences in intensity-modulated proton therapy (IMPT) using pencil beam scanning technology and photon-based radiotherapy (IMRT) hypofractionated whole-breast irradiation (HF-WBI) find out more beneficial technique. Methods Materials Eight breast cancer (BC) patients with pathological stage T1 ~ 2N0M0 were immobilized underwent 4D-CT used d...

background: to evaluate the dosimetric difference between conventional and three-dimensional conformal radiotherapy (3d-crt) using 6 and 18 mv x-ray photons. materials and methods: computed tomography scans of 26 pelvic patients were acquired and transferred to the 3d treatment planning system. for each patient, 8 conventional plans (3, 4, 5 and 6 fields) and one 3d-crt plan were prepared using...