نتایج جستجو برای: double strand
تعداد نتایج: 262569 فیلتر نتایج به سال:
Influence of chromatin structure on the induction of DNA double strand breaks by ionizing radiation.
Pulsed field gel electrophoresis was used to examine the influence of chromatin structure on the induction of DNA double strand breaks by gamma-irradiation in CHO-WBL cells, nuclei, and a series of protein-depleted chromatin substrates. We developed a method to isolate intact nuclei in agarose plugs that avoids DNA shearing and nucleolytic degradation during sample preparation, and facilitates ...
[This corrects the article DOI: 10.1371/journal.pgen.0030110.].
Cytokines are subdivided in 12 sub-families and are described as multi-functional molecules that play an important biological activity in host defense system against pathogens, in homeostasis, tissue repair, cell growth and development. CytokineDB is an annotated database that collects biological information regarding the cytokines family in human and will be periodically updated by including n...
We propose a new way of using geometric transitions to study metastable vacua in string theory and certain confining gauge theories. The gauge theories in question are N = 2 supersymmetric theories deformed to N = 1 by superpotential terms. We first geometrically engineer supersymmetry-breaking vacua by wrapping D5 branes on rigid 2-cycles in noncompact Calabi-Yau geometries, such that the cent...
Werner syndrome is an autosomal recessive accelerated-aging disorder caused by a defect in the WRN gene, which encodes a member of the RecQ family of DNA helicases with an exonuclease activity. In vitro experiments have suggested that WRN functions in several DNA repair processes, but the actual functions of WRN in living cells remain unknown. Here, we analyzed the kinetics of the intranuclear ...
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