نتایج جستجو برای: drug metabolism

تعداد نتایج: 792396  

Journal: :Folia Pharmacologica Japonica 2009

Journal: :Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi) 1966

Journal: :International Journal of Molecular Sciences 2012

Journal: :Journal of Chemical Education 1962

2009
James Corey Adams Michael J. Keiser Li Basuino Henry F. Chambers Deok-Sun Lee Olaf G. Wiest Patricia C. Babbitt

Small molecule drugs target many core metabolic enzymes in humans and pathogens, often mimicking endogenous ligands. The effects may be therapeutic or toxic, but are frequently unexpected. A large-scale mapping of the intersection between drugs and metabolism is needed to better guide drug discovery. To map the intersection between drugs and metabolism, we have grouped drugs and metabolites by ...

Journal: :AACN advanced critical care 2017
Uyen Diep Melissa Chudow Katlynd M Sunjic

P harmacokinetics is a term that describes the time course and fate of a drug in the body. The term encompasses drug absorption, distribution, metabolism, and elimination and is often referred to as drug disposition.1 Absorption is defined as the process by which a drug enters the systemic circulation, distribution is the movement of the drug between body compartments, and metabolism encompasse...

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