Today's multiple food manipulations may interact to produce a wide-spread difficult-toidentify synergistic malnutrition presenting as a highly idiosyncratic substrate-cat alystantinutrient vitamin-resistant Hoffer-type pellagra-beriberi mainly afflicting primates and accounting for the medically dominant modernization disease syndrome as a variant of the classical catalytic B vitamin-sensitive ...

The concept of a positive agent, such as a bacterium or virus, a chemical substance, or a physical agent, producing injury to tissue is so well ingrained in medical thought that it has actually hindered our understanding of the whole problem of avitaminosis. Especially is this true in the more restricted field of the vitamins that are responsible for the maintenance of the health of the nervous...

CONTEXT AND OBJECTIVES In July 2009, WHO and partners were notified of a large outbreak of unknown illness, including deaths, among African Union (AU) soldiers in Mogadishu. Illnesses were characterized by peripheral edema, dyspnea, palpitations, and fever. Our objectives were to determine the cause of the outbreak, and to design and recommend control strategies. DESIGN, SETTING, AND PARTICIP...

There is increasing evidence that the biological function of vitamin B1 is concerned with oxidative processes in the living organism. In studies of oxygen utilization by manometric methods, Peters and his coworkers (1, 2) have shown that there is increased oxygen uptake by deficient brain and kidney tissues in vitro following the addition of vitamin B1. In the same laboratory Thompson and Johns...

the rice, and also that the wheat atta used in Calcutta is so finely sifted that it is also deprived of these ingredients even to a greater extent than the rice. (7) Pigeons feci on polished rice, boiled and unboiled, suffer from loss of weight and from a characteristic polyneuritis. (8) The severe outbreaks of this disease in Calcutta in 1877-79 and 1907-09 are correlated with a high price of ...

It would prolong tliia already lengthy paper unduly were I to enter on a discussion of that protean malady, beri-beri, with the literature of which I have pretty fully acquainted myself, or to refer to other epidemics of dropsy which have been described as prevailing in Brazil and elsewhere. I beliSve that the term beri-beri has been applied to a number of different diseased conditions, and tha...