Objectives This retrospective study evaluated whether the use of additional anterior 99mTc-sestamibi/123I pinhole imaging improves the outcome of 99mTc-sestamibi/123I subtraction SPECT/CT in parathyroid scintigraphy (PS). Materials and Methods PS using simultaneous dual-isotope subtraction methods and an acquisition protocol combining SPECT/CT and planar pinhole imaging was performed for 175 ...

Many solid tumors contain an overabundance of phospholipid ethers relative to normal cells. Capitalizing on this difference, we created cancer-targeted alkylphosphocholine (APC) analogs through structure-activity analyses. Depending on the iodine isotope used, radioiodinated APC analog CLR1404 was used as either a positron emission tomography (PET) imaging ((124)I) or molecular radiotherapeutic...

The development of dual-imaging enabled cancer-targeting nanoparticles (DICT-NPs) is reported based on newly developed biodegradable photoluminescent polymers and superparamagnetic iron oxide nanoparticles. DICT-NPs possess capabilities of dual-imaging (magnetic resonance imaging and optical imaging), magnetic targeting, and potentially selective targeting for cancer cells. The development of D...

PURPOSE In the effort to reduce radiation exposure to patients undergoing myocardial perfusion imaging (MPI) with SPECT/CT, we evaluate the feasibility of a single CT for attenuation correction (AC) of single-day rest (R)/stress (S) perfusion. METHODS Processing of 20 single isotope and 20 dual isotope MPI with perfusion defects were retrospectively repeated in three steps: (1) the standard m...

The GATE package is used to perform Monte Carlo hadrontherapy simulations of a cancer treatment combined with the complete description of an associated positron emission tomography (PET) imaging device for dose monitoring. This study aimed to demonstrate that the GATE platform has the capability to perform realistic simulations in the field of hadrontherapy, combining both dose and imaging syst...

temporal bone chondroblastoma is an extremely rare benign bone tumor. we encountered two cases showing similar imaging findings on computed tomography (ct), magnetic resonance imaging (mri), and dual-time-point 18f-fluorodeoxyglucose (18f-fdg) positron emission tomography (pet)/ct. in both cases, ct images revealed temporal bone defects and sclerotic changes around the tumor. most parts of the ...

The role of various radionuclide investigations, including parathyroid scintigraphy, bone scintigraphy and serum parathormone estimations in the diagnosis of primary hyperparathyroidism is reviewed briefly. The initial experience with the dual isotope (Tl-201; Tc-99m) subtraction scintigraphy for the preoperative localization of parathyroid adenomas is presented (JPMA 37 : 237, 1987).

We present a novel stereo imaging technique called dualfocus stereo imaging or DFSI. DFSI uses a pair of images captured from different viewpoints and at different foci, but with identical wide aperture size. Each image in an DFSI pair exhibits different defocus blur, and the two images form a defocused stereo pair. To model defocus blur, we introduce a defocus kernel map (DKM) that computes th...