The evaluation of HER2 status in invasive breast carcinoma can be performed by multiple methods. We assessed the feasibility of performing 2 of these, chromogenic in situ hybridization (CISH) and immunohistochemical staining, on single tissue sections of breast carcinoma. During assay development, sequential performance of immunohistochemical staining after CISH resulted in weaker HER2 expressi...

In this paper, we introduce the concept of $g$-dual frames for Hilbert $C^{*}$-modules, and then the properties and stability results of $g$-dual frames  are given.  A characterization of $g$-dual frames, approximately dual frames and dual frames of a given frame is established. We also give some examples to show that the characterization of $g$-dual frames for Riesz bases in Hilbert spaces is ...

The principal advantages of simultaneously recording from, and staining of single neurons, buried deep in tissue, is obvious and need not be stressed. Particularly in insects, where most cell somata are electrically silent, there is so far no way to correlate neuronal activity with a particular cell other than to penetrate and to label small fibers simultaneously (Hengstenberg, 1971). Great eff...

Semiconductor nanocrystals were prepared for use as fluorescent probes in biological staining and diagnostics. Compared with conventional fluorophores, the nanocrystals have a narrow, tunable, symmetric emission spectrum and are photochemically stable. The advantages of the broad, continuous excitation spectrum were demonstrated in a dual-emission, single-excitation labeling experiment on mouse...