Carbon dioxide (CO2) is an American Veterinary Medical Association approved swine euthanasia method. A limitation for the use of CO2 during depopulation events, such as a foreign animal disease diagnosis, ability to apply method finisher and adult pigs. The common methods in finishing require individual handling restraint, increasing human safety risk large-scale events. This project validates ...

Determination of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in fly ash and cinders collected from nine municipal incinerators in Japan was made. The concentrations of PCDDs and PCDFs in this study were generally in the same range as those in Europe and North America. However, the rather different congener composition compared with those published already...

As we saw last week, the worldwide scientific community has reached consensus that global warming is inevitable if humans continue to dump "greenhouse gases" into the atmosphere at anything like present rates. Greenhouse gases include carbon dioxide, methane, nitrous oxide, chlorofluorocarbons (CFCs) and a few others. These gases act like the glass covering a greenhouse, letting sunlight in but...

The thymidylate synthase inhibitor 5-fluorouracil (5-FU) continues to play a pivotal role in the treatment of cancer. A downstream event of thymidylate synthase inhibition involves the induction of a self-defeating base excision repair process. With the depletion of TTP pools, there is also an increase in dUMP. Metabolism of dUMP to the triphosphate dUTP results in elevated pools of this atypic...

The crystal structures of a deletion mutant of human thymidylate synthase (TS) and its ternary complex with dUMP and Tomudex have been determined at 2.0 A and 2.5 A resolution, respectively. The mutant TS, which lacks 23 residues near the amino terminus, is as active as the wild-type enzyme. The ternary complex is observed in the open conformation, similar to that of the free enzyme and to that...

If typical host plants are absent, some herbivorous insects “dump” eggs on unsuitable substrates, even though this can cause complete larval mortality and reduced maternal life span. In the seedbeetleCallosobruchusmaculatus (F.) (Coleoptera:Chrysomelidae: Bruchinae), the tendency to dump eggs varies genetically both within and between populations. A previous study hypothesized that egg-dumping ...

The thymidylate synthase inhibitor 5-fluorouracil (5-FU) continues to play a pivotal role in the treatment of cancer. A downstream event of thymidylate synthase inhibition involves the induction of a self-defeating base excision repair process. With the depletion of TTP pools, there is also an increase in dUMP. Metabolism of dUMP to the triphosphate dUTP results in elevated pools of this atypic...

The Digital Imaging and Remote Sensing Laboratory (DIRS) at the Rochester Institute of Technology, along with the Savannah River National Laboratory is investigating passive methods to quantify vehicle loading. The research described in this paper investigates multiple vehicle indicators including brake temperature, tire temperature, engine temperature, acceleration and deceleration rates, engi...

The RTH flotation tailing dump, located in the old open pit Bor about 500 m southeast of Flotation Plant, has been continuous operational work since 1985. flotations dumps are important mining facilities that constantly changed during their exploitation period. Due to changes occurring dump its exploitation, it is necessary perform a technical and technological surveillance-auscultation order c...