BACKGROUND Family environment plays an important role in the intergenerational transmission of major depressive disorder (MDD), but less is known about how day-to-day mother-child interactions may be disrupted in families with a history of MDD. Disruptions in mother-child synchrony, the dynamic and convergent exchange of physiological and behavioral cues during interactions, may be one importan...

In this study we report about two novel azomethine–BODIPY dyads 1 and 2. The two dyads have been, respectively, synthesized by covalent tethering of tautomeric ortho-hydroxy aromatic azomethine moieties including N-salicylideneaniline (SA) and N-naphthlideneaniline (NA) to a BODIPY fluorophore. Both of the two dyads 1 and 2 show enol-imine (OH) structures dominating in the crystalline state. Dy...

BACKGROUND Few trials have examined long-term outcomes of advance care planning (ACP) interventions. We examined the efficacy of an ACP intervention on preparation for end-of-life decision making for dialysis patients and surrogates and for surrogates' bereavement outcomes. STUDY DESIGN A randomized trial compared an ACP intervention (Sharing Patient's Illness Representations to Increase Trus...

The catalytic and regulatory polypeptide chains of Escherichia coli aspartate transcarbamoylase are encoded by the pyrB and pyrI genes, respectively, which constitute a single transcriptional unit in the pyrBI operon. The DNA sequence immediately preceding the first structural gene, pyrB, contains a short open reading frame that could encode a 44-amino acid leader peptide and a (G+C)-rich regio...

In many domains, imitating others’ behaviour can help individuals to solve problems that would be too difficult or complex for the individuals. collective decision making tasks, people have been shown use confidence as a means communicate uncertainty surrounding internal noisy estimates. Here, we show alignment, namely, shifting average between dyad members towards each other, naturally emerges...

Collaboration is generally an effective means of learning new information, but is collaboration productive in domains where collaborators may hold qualitatively different conceptions of the domain’s causal structure? We explored this question in the domain of evolutionary biology, where previous research has shown that most individuals construe evolution as the uniform transformation of an enti...

In this paper we present a novel dimensional synthesis technique for approximate motion synthesis of spherical kinematic chains. The methodology uses an analytic representation of the spherical RR dyad’s workspace that is parameterized by its dimensional synthesis variables. A two loop nonlinear optimization technique is then employed to minimize the distance from the dyad’s workspace to a fini...