because of participation in many aspects of human life, and due to oxidation-sensitive characteristics of dopamine (da) and arachidonoyl dopamine (aa-da), the necessity of biocompatible carrier to keep them against oxidation is of importance. in this work, we explored the putative binding sites of da and aa-da to -lactoglobulin (blg) as potent carrier. docking results identified the binding si...

Marine biogeochemistry refers to the processes associated with the planktonic ecosystem of the ocean. These are central to nutrient, carbon, and energy cycling, as well as providing the basis of the marine food chain. The field is being revolutionized by new data types and observing platforms, as well as by improvements in ocean modelling brought about by increasing computer power. To further o...

A major hypothesis in addiction research is that alcohol induces neuroadaptations in the mesolimbic dopamine (DA) system and that these neuroadaptations represent a key neurochemical event in compulsive drug use and relapse. Whether these neuroadaptations lead to a hypo- or hyperdopaminergic state during abstinence is a long-standing, unresolved debate among addiction researchers. The answer is...

Domoic acid (DA), a neurotoxin, is produced by marine algae and has caused toxications worldwide in animals and humans. However, the toxicokinetics of DA have not been fully evaluated, and information is missing on the disposition of DA following oral exposures at doses that are considered safe for human consumption. In this study, toxicokinetics of DA were investigated in cynomolgus monkeys fo...

Twelve providers (eight institutions) participating in a Gender and Sex Diversity Fertility Working Group completed a survey assessing their hospital's transgender, disorders/differences of sex development (DSD), and fertility healthcare teams. Participants also prioritized the development of a: (1) Provider Assessment Tool (questionnaire assessing knowledge/feelings about future fertility), or...

background: developmental dysplasia of hip (ddh) is a common childhood disorder, and ultrasonography examination is routinely used for screening purposes. in this study, we aimed to evaluate a modified combined static and dynamic   ultrasound technique for the detection of ddh and to compare with the results of static and dynamic ultrasound techniques.       methods: in this cross-sectional stu...

Dopamine  (DA)  and  uric  acid  (UA)  are  two  of  important bimolecular widely  circulated  in  body blood. Therefore, development of simple and rapid methods for simultaneous determination of them in  routine  analysis  has  a  great  significance  for  many  researchers. Therefore,  for  the  first  time, nanocomposite  of  graphene  (Gr)LaMnO3has  been  utilized  to  fabricate  the  new  ...

Dopamine (DA) is implicated in many behaviors, including motor function, cognition, and reward processing; however, the role of DA in fear processing remains equivocal. To examine the role of DA in fear-related learning, dopamine-deficient (DD) mice were tested in a fear-potentiated startle paradigm. DA synthesis can be restored in DD mice through administration of 3, 4-dihydroxy-l-phenylalanin...

The effect of substances which alter extracellular dopamine (DA) concentration has been studied by measuring changes in the binding of radiolabelled raclopride, a DA D2 receptor ligand that is sensitive to endogenous DA. To better characterize the relationship between extracellular DA concentration and DA D2 receptor binding of raclopride, we compared the changes of extracellular DA concentrati...

Abstract In this study, the potential impacts of dynamic assessment (DA) and non-dynamic (non-DA) on Ethiopian EFL students’ productive skills were investigated. Additionally, study examined attitudes regarding using DA in their speaking writing classes. Fifty-three intermediate learners selected convenience sampling method separated into two groups order to accomplish these goals. Next, both p...