BACKGROUND Monocytes/macrophages play a central role in many stages of development of atherosclerotic plaques, including the conversion to an unstable morphology with rupture and fissuring. A better understanding of the mechanism of attachment of monocytes to activated endothelial cells would prove useful in developing strategies aimed at blocking this initial step. Here we describe a novel in ...

Acute peritonitis is a frequent medical condition that can trigger severe sepsis as a life-threatening complication. Neutrophils are first-responders in infection but recruitment mechanisms to the abdominal cavity remain poorly defined. Here, we demonstrate that high endothelial venules (HEVs) of the greater omentum constitute a main entry pathway in TNFα-, Escherichia coli (E. coli)- and caeca...

Sec6/8 (exocyst) complex regulates vesicle delivery and polarized membrane growth in a variety of cells, but mechanisms regulating Sec6/8 localization are unknown. In epithelial cells, Sec6/8 complex is recruited to cell-cell contacts with a mixture of junctional proteins, but then sorts out to the apex of the lateral membrane with components of tight junction and nectin complexes. Sec6/8 compl...

Stem bromelain, a cysteine protease isolated from pineapples, is a natural anti-inflammatory treatment, yet its mechanism of action remains unclear. Curious as to whether bromelain might affect selectin-mediated leukocyte rolling, we studied the ability of bromelain-treated human neutrophils to tether to substrates presenting immobilized P-selectin or E-selectin under shear stress. Bromelain tr...

The Internet-based recruiting platforms become a primary recruitment channel in most companies. While such platforms decrease the recruitment time and advertisement cost, they suffer from an inappropriateness of traditional information retrieval techniques like the Boolean search methods. Consequently, a vast amount of candidates missed the opportunity of recruiting. The recommender system tech...

PT Kereta Api Indonesia (Persero) merupakan salah satuBadan Usaha Milik Negara (BUMN) yang bergerak di bidang jasa transportasi pengangkutan penumpang dan barang, negosiasi peti kemas menggunakan kereta api. Dalam proses bisnis pada perusahaan, SAP sebagai aplikasi utama, disamping itu terdapat e-Recruitment digunakan untuk mendukung khususnya penerimaan karyawan. penggunaan kedua permasalahan ...

0378-1127/$ see front matter 2011 Elsevier B.V. A doi:10.1016/j.foreco.2011.07.011 ⇑ Corresponding author. E-mail address: [email protected] (B. Young). This study empirically evaluates and maps the relationships between recruitment and species and tree size diversity, as measured with the Shannon’s index, within mixed poplar/birch and mixed spruce stands across the boreal forest of Alaska. Da...