نتایج جستجو برای: ectrodactyly

تعداد نتایج: 300  

2013
Karen Banks

This Article, in Parts I-III, traces the development of Articles 85 and 86 of the EEC Treaty from the drafting of the Treaty, through discussions in the 1960s on their possible application to mergers, to the Continental Can case in 1973 and its subsequent interpretation. Part IV examines the Commission’s proposal for a regulation on the control of concentrations between undertakings. Part V exp...

Journal: :Cell 1999
Jacopo Celli Pascal Duijf Ben C.J Hamel Michael Bamshad Bridget Kramer Arie P.T Smits Ruth Newbury-Ecob Raoul C.M Hennekam Griet Van Buggenhout Arie van Haeringen C.Geoffrey Woods Anthonie J van Essen Rob de Waal Gert Vriend Daniel A Haber Annie Yang Frank McKeon Han G Brunner Hans van Bokhoven

EEC syndrome is an autosomal dominant disorder characterized by ectrodactyly, ectodermal dysplasia, and facial clefts. We have mapped the genetic defect in several EEC syndrome families to a region of chromosome 3q27 previously implicated in the EEC-like disorder, limb mammary syndrome (LMS). Analysis of the p63 gene, a homolog of p53 located in the critical LMS/EEC interval, revealed heterozyg...

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