There are some evidences regarding anti-allergic and anti-inflammatory effects of Licorice common in traditional medicine and its usefulness in Diabetes mellitus and Diabetes insipidus and its stimulatory effect on admeocortical gland. This medicinal plant contains glycyrrhizin, sterogenic substances, cumarins, flavonoids, sterols, choline, asparagine and glaberin. Glycyrrhizin and glaberin hav...

The functional changes in respiration, circulation, blood composition and blood temperature were investigated in anesthetized dogs that were subjected to the inhalation of steam. The pathogenesis of the accompanying pulmonary congestion and edema was analyzed by measurements of: (a) pulmonary blood flow, (b) pressures in pulmonary artery and vein, (c) pulmonary blood (P32) volume, (d) electrica...

The functional changes in respiration, circulation, blood composition and blood temperature were investigated in anesthetized dogs that were subjected to the inhalation of steam. The pathogenesis of the accompanying pulmonary congestion and edema was analyzed by measurements of: (a) pulmonary blood flow, (b) pressures in pulmonary artery and vein, (c) pulmonary blood (P32) volume, (d) electrica...

Myocardial interstitial edema forms as a result of several disease states and clinical interventions. Acute myocardial interstitial edema is associated with compromised systolic and diastolic cardiac function and increased stiffness of the left ventricular chamber. Formation of chronic myocardial interstitial edema results in deposition of interstitial collagen, which causes interstitial fibros...

Introduction: Black pepper (Piper nigrum L.) is one of the medicinal plants being used to prevent and manage stroke in Persian Medicine. Current findings support its anti-inflammatory, radical scavenging and neuroprotective characteristics. In this study, we aimed to evaluate role of black pepper on functional and histopathological outcomes of stroke in an animal model of MCAO. Materials and Me...

BACKGROUND AND PURPOSE Reports of improved short-term (less than 72 hours) outcome in experimental models of mechanical and ischemic central nervous system injury suggest that exogenous ganglioside administration may confer a protective effect on neural tissue. We studied the effect of the monosialoganglioside GM1 on cerebral infarction and edema in spontaneously hypertensive rats subjected to ...

INTRODUCTION Mechanical ventilators are increasingly used in critical care units. However, they can cause lung injury, including pulmonary edema. Our previous studies indicated that γ-aminobutyric acid (GABA) receptors are involved in alveolar-fluid homeostasis. The present study investigated the role of GABA receptors in ventilator-induced lung injury. METHODS Adult female Sprague-Dawley rat...

BACKGROUND Cerebral edema is a major threat for stroke victims. Most studies have focused on the neuroprotective activities of propofol, addressing infarct volume rather than cerebral edema. Aquaporin-4 (AQP4) plays an important role in maintaining brain water homeostasis under various neurological insults. We explored the effect of propofol pretreatment on cerebral edema in a rat model of brai...

BACKGROUND AND PURPOSE The prognosis of spontaneous intracerebral hemorrhage (sICH) is poor because of the mass effect arising from the hematoma and the associated peri-hemorrhagic edema, leading to increased intracranial pressure. Because the efficacy of surgical and anti-edematous treatment strategies is limited, we investigated the effects of mild induced hypothermia in patients with large s...

Increasing evidence indicates that physical activity reduces brain damage after stroke. The purpose of this study was to determine whether exercise-induced neuroprotection is associated with improved brain integrity in stroke. Adult male Sprague-Dawley rats (3 months old, n=38) exercised on a treadmill, which required repetitive locomotor movement, for 30 minutes each day for 3 weeks. Then, usi...