Transcriptomic studies help to further our understanding of gene function. Human transcriptomic studies tend to focus on a particular subset of tissue types or a particular disease state; however, it is possible to collate into a compendium multiple studies that have been profiled using the same expression analysis platform to provide an overview of gene expression levels in many different tiss...

The solvation of alanine is investigated, with a focus on adding a sufficient number of discrete water molecules to determine the first solvation shell for both the nonionized (N) and zwitterionic (Z) forms to converge the enthalpy of solvation and the enthalpy difference for the two forms of alanine. Monte Carlo sampling was employed using the generalized effective fragment potential (EFP) met...

This paper is concerned with the performance evaluation of loss networks. For the simplest networks there are explicit analytical formulae for the important measures of performance , but for networks which involve some level of dynamic control, exact analytical methods have had only limited success. Under several regimes the Erlang Fixed Point (EFP) method provides a good approximation for the ...

The Ecological Footprint (EFP) is a useful indicator for assessing the progress of environmental performance and offers solid basis sustainability studies. In this paper, we contribute to broadening its possibilities investigation by measuring cross-country links in EFP global hectares per capita. modeling framework based on dynamic factor analysis estimate, parametric form, an index that provi...

Effective fragment potential (EFP) molecular modeling approaches have been applied for the first time to the rational design of molecularly imprinted polymers for the group recognition of selected polychlorinated biphenyls (PCBs). EFP calculations were benchmarked using the S22 compound test set and returned energies within 1 kcal mol(-1) of the reported gold standard CCSD(T) approach, but with...

The effect of pre and post-anthesis shading (20% of incident radiation) on pericarp development, cotyledon cell number and seed growth dynamic of fruits from three positions in the capitulum (peripheral, mid and central) of two sunflower (Helianthus annuus L.) genotypes were studied at two locations. Both shading treatments reduced pericarp weight, fruit volume and total yield per plant. Plants...

The factors affecting glomerular ultrafiltration with elevated ureteral pressure were examined in both plasma-expanded (2.5% body weight) and hydropenic Munich-Wistar rats. Elevated ureteral pressure (20 mm Hg) alternated as the initial condition in both groups. Glomerular capillary hydrostatic pressure (PG) and Bowman's space pressure (Pt) were measured directly in surface glomeruli with a ser...

Structure and bonding patterns in tert-butanol (TBA)−water mixtures are investigated by using molecular dynamics simulations with the effective fragment potential (EFP) method. EFP is a model potential in which all parameters are obtained from a set of ab initio calculations on isolated fragment molecules. Mixed-basis EFP potentials (called “EFPm”) for water and TBA molecules were prepared and ...