AIM To discover single nucleotide polymorphisms (SNPs) in the promoter region of angiotensin II type 1 receptor (AT1) gene and evaluate their associations with the occurrence of essential hypertension (EH) and coronary heart disease (CHD) in Chinese Han population. METHODS SNPs detection was performed by PCR-sequencing. The genotype was determined by the same method in a total number of 473 u...

BACKGROUND Peroxisome proliferator-activated receptor gamma (PPARG) plays an important role in the pathogenesis and maintenance of essential hypertension (EH). It has been suggested that polymorphisms of PPARG are associated with the risk of EH. However, findings to date remain controversial. To elucidate the associations between the PPARG Pro12Ala and C161T polymorphisms and EH risk, a meta-an...

Cerebrospinal fluid (CSF) and plasma dopamine-beta-hydroxylase (DBH) activity was measured in 22 normotensive (NT), 31 essential hypertensive (EH), and 11 renal hypertensive (RH) patients. Although no differences were observed in their plasma DBH, the mean CSF-DBH activity and specific activity of EH were significantly lower than those of NT and RH patients. Very low CSF-DBH (less than 0.15 uni...

To properly characterize several isolates of Paecilomyces fumosoroseus, a fungal entomopathogen of whiteflies (Homoptera: Aleyrodidae) and other insect pests for biocontrol purposes, virulence towards Trialeurodes vaporariorum, and subtilisin-like (Pr1) and trypsin-like (Pr2) protease activity during propagule production were investigated in monospore cultures (MCs). The virulence of three MCs ...

From the perspective of time domain and frequency domain, we investigate energy harvesting cognitive radio networks (EH-CRNs) with multichannel, where secondary transmitter (ST) opportunistically accesses licensed subchannels to transmit packets by consuming harvested energy. To explore spectrum holes improve lifetime EH-CRNs, ST scavenges from radio-frequency (RF) signal in wide band during (E...

the pathophysiology of primary benign exertional headache (eh) is not still clearly defined. some researchers have suggested an impaired vascular response as the etiology of this disorder. in this study we investigated whether there are any differences in blood pressure (bp) and heart rate (hr) of the subjects in course of the static and dynamic exercises and the treadmill stress test between t...

Myomesin is the most prominent structural component of the sarcomeric M-Band that is expressed in mammalian heart and skeletal muscles. Like titin, this protein is an intracellular member of the Ig-fibronectin superfamily, which has a flexible filamentous structure and which is largely composed of two types of domain that are similar to immunoglobulin (Ig)-like and fibronectin type III (FNIII) ...

The aim of the present study was to examine whether single-nucleotide polymorphisms (SNPs) of β1 subunit of large-conductance Ca2+-activated K+ channel (KCNMB1) and inwardly rectifying K+ channel, subfamily J, member-11 (KCNJ11) are associated with essential hypertension (EH) in Xinjiang Kazak Chinese patients. A polymerase chain reaction-restriction fragment length polymorphism technique was a...

BACKGROUND Hypertension, including essential and secondary hypertension, is a multifactorial disease, affecting more than one billion people worldwide. Secondary hypertension can result from mutations of cullin-3 (CUL3); however, whether polymorphisms of CUL3 are associated with essential hypertension (EH) has not been reported. Here, we investigated the association between CUL3 SNPs rs17479770...

Sediment redox potentials (EH) at stations of different trophic status in the central Adriatic from 2001-2007 were investigated in this paper. For most part of the year at open sea and channel stations EH values were mainly positive (+150 to 0 mV), even to 10 cm sediment depth. Positive EH (absence of sulphate reduction with very low sulphide concentrations) at these stations is probably caused...