OBJECTIVE To compare the outcomes (auditory threshold and open-set speech perception at 48-month follow-up) of a new near-field monitoring procedure, electrical compound action potential, on positioning the auditory brainstem implant electrode array on the surface of the cochlear nuclei versus the traditional far-field electrical auditory brainstem response. STUDY DESIGN Retrospective study. ...

The biologically derived hydrogel Matrigel (MG) was used to coat a Parylene-based sheath intracortical electrode to act as a mechanical and biological buffer as well as a matrix for delivering bioactive molecules to modulate the cellular response and improve recording quality. MG was loaded with dexamethasone to reduce the immune response together with nerve growth factor (NGF) and brain-derive...

Background: The cellular basis for the monophasic action potential (MAP) has long been a matter of debate. At the center of the controversy is the issue as to which of the two electrodes is the recording electrode and which is the indifferent electrode. The present study is designed to address this issue. Methods: Transmembrane action potentials (TAPs) and either intramural MAPs or contact (Fra...

This methodological paper provides a detailed description of a novel ultralowABSTRACT noise preand main-amplifi er system designed for the extracellular recording of voltage spikes produced by neuronal action potentials. The main diffi culties with extracellular recording are the unwanted electrical signals that lower the recording quality. They include destructive interferences by alternating ...

BACKGROUND The cellular basis for the monophasic action potential (MAP) has long been a matter of debate. At the center of the controversy is the issue as to which of the two electrodes is the recording electrode and which is the indifferent electrode. The present study is designed to address this issue. METHODS Transmembrane action potentials (TAPs) and either intramural MAPs or contact (Fra...

There is no uniformity in the published literature from different laboratories on the optimal electrode configuration for recording nerve action potentials, and a number of standard texts omit any reference to the effects that interelectrode distance and electrode orientation can have on the shape, amplitude and latency of nerve action potentials. The sensory action potential from the digital n...

An implantable electrode assembly consisting of collagen and metallic electrodes was constructed to measure simultaneously neural signals from the intact nerve and bioelectrical noises in awake animals. Mechanical artifacts, due to bodily movement, were negligibly small. The impedance of the collagen electrodes, measured in awake cats 6-7 days after implantation surgery, ranged from 39.8-11.5 k...