For the majority of patients with pulmonary embolism the recommended therapy consists of a 5 to 7 day treatment with heparin followed by a treatment with oral anticoagulants given for at least 3 months. The currently recommended duration of oral anticoagulant treatment for pulmonary embolism is the result of the balance between the benefit provided by treatment, essentially the prevention of re...

The management of patients with acute pulmonary embolism is made challenging by its wide spectrum of clinical presentation and outcome, which is mainly related to patient haemodynamic status and right ventricular overload. Mechanical embolic obstruction and neurohumorally mediated pulmonary vasoconstriction are responsible for right ventricular overload. The pathophysiology of acute pulmonary e...

background: safe exclusion and risk stratification are currently recommended for the initial management of patients with acute pulmonary embolism (ape). the aim of this study was to assess the safe exclusion and risk stratification value of d-dimer (dd) for ape when tested at the beginning of admission. materials and methods: all consecutive chinese ape patients and controls were recruited from...

Predisposing Factors in Cardiogenic Cerebral Embolism To the Editor: I read with interest the article by Yasaka and associates' on the pathophysiology of intracardiac thrombus formation in patients with recurrent cerebral embolism. However, I was surprised that there were no cases found or mention made of either paradoxical embolism or atrial septal aneurysm as predisposing factors of recurrent...

Pulmonary embolism is a blockage of main artery or one of its branches of lung by the fat, amniotic fluid, embolisation of air or any other foreign substances. It is also due to formation of thrombus [blood clot] in the arteries of lung. Due to the pulmonary embolism the blood circulation in the body will be effected. Sometimes PE leads to death also by the lacking of breathing. In USA the annu...

REFERENCES 1 Moores L, Zamarro C, Gómez V, et al. Changes in PESI score predict mortality in intermediate-risk patients with acute pulmonary embolism. Eur Respir J 2013; 41: 354–359. 2 Aujesky D, Smith KJ, Cornuz J, et al. Cost-effectiveness of lowmolecular-weight heparin for treatment of pulmonary embolism. Chest 2005; 128: 1601–1610. 3 Erkens PM, Gandara E, Wells PS, et al. Does the Pulmonary...

OBJECTIVE Pulmonary embolism is an underdiagnosed major cause of death for hospitalized patients. The objective of this study was to identify the conditions associated with fatal pulmonary embolism in this population. METHODS A total of 13,074 autopsy records were evaluated in a case-control study. Patients were matched by age, sex, and year of death, and factors potentially associated with f...

Pulmonary embolism may be a life-threatening condition that needs immediate medical intervention. Early detection plays an important role in improving the survival rate. However, pulmonary embolism is a difficult diagnosis that may be missed because of non-specific clinical presentation. According to guidelines on the diagnosis and management of acute pulmonary embolism, it should be diagnosed ...

PURPOSE OF REVIEW Until recently, little was known about the long-term outcome of pulmonary embolism. Long-term mortality and recurrence rates, the case fatality rate of recurrent events, and the frequency of persistent vascular defects remained largely unknown. Improvements in our knowledge of these aspects may help to define the optimal long-term treatment of pulmonary embolism. This review w...

OBJECTIVES To determine the association between physical inactivity (that is, a sedentary lifestyle) and incident idiopathic pulmonary embolism. DESIGN Prospective cohort study. SETTING Nurses' Health Study. PARTICIPANTS 69 950 female nurses who completed biennial questionnaires from 1990 to 2008. Main outcome measures The primary outcome was idiopathic pulmonary embolism confirmed in med...