The aim of this study was to prepare surfactant free Diclofenac sodium loaded ethyl cellulose nanoparticles by O/W single emulsion solvent evaporation high pressure homogenization technique.In the preparation of O/W single emulsion sodium alginate used as an emulsifying/stabilizing agent. Microparticles of nine different batches at different condition were prepared after that optimized batch wa...

Using recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) as a model drug, the present study demonstrated a practically feasible process to produce polymeric microspheres for sustained-release delivery of protein drugs with preserved integrity. This process is featured with pre-loading proteins into polysaccharide fine particles via a self-standing aqueous-aqueous "emu...

We present an approach to fabricate capsules consisting of a composite layer of particles and block copolymers . The capsules are fabricated by directed assembly of block copolymers at the interfaces of a double emulsion template and electrostatic adsorption of particles onto the copolymers. The double emulsion drops are prepared using capillary-based microfluidics. The solvent phase of the dou...

Diclofenac sodium is a Non-Steroidal Anti-inflammatory Drug, active against relief from pain and inflammation. The main objective of this research work was to prepare Ethyl Cellulose microsphere loaded with Diclofenac and invitro drug release study. In the present study, emulsion Solvent Evaporation Method is used for preparing microsphere. The polymer (EC) and drug (Diclofenac Sodium) was diss...

Nanoparticles were obtained by nanoprecipitation and emulsion solvent evaporation (ESE) method. In the ESE method, size of particles depended on type concentration surfactant (in water phase) polymer organic phase). The best results with ionic surfactants, however, use such compounds may accelerate degradation process polymers. ratio (methylene chloride) to non-solvent (hexane) has a significan...

Here, we prepared hydrophobic cryogel particles with monolithic supermacropores based on poly-trimethylolpropane trimethacrylate (pTrim) by combining the inverse Leidenfrost effect and cryo-polymerization technique. The adopting this method demonstrated separation of stabilized O/W emulsion surfactant. were characterized in terms macroscopic shape porous structure. It was found that had a narro...

Magnetic resonance imaging is used to study changing microstructure and molecular motion during dissolution of poly(vinyl alcohol) (PVA) in water. One-dimensional water concentration profiles were measured as a function of distance from the polymer-solvent interface. Diffusion-weighted profiles were used to calculate the spatial variation of the self-diffusion coefficient of water. The results ...

Organic semiconductor nanoparticles provide a potentially scalable approach for photovoltaics that can be processed from aqueous media. Particles of poly(3-hexylthiophene) (P3HT):phenyl-C61-butyric acid methyl ester (PCBM) were prepared using two techniques; those produced by a mini-emulsion method contained greater amounts of crystalline P3HT domains with charge generation resembling phase-sep...

A solution-processed patterning of functional organic materials in emulsion is reported. The concept is to absorb microdrops onto predefined locations by hydrophilicity difference. Owing to a universal solvent used, the method can be applied to pattern variety materials on substrates of interest over large size. The figure shows Rhodamine 6G patterned film.